Nephrolithiasis Clinical Trial
Official title:
The Effect of mu Opioid Receptor Polymorphism on the Response to Alfentanil During Lithotripsy
The response to opioids varies greatly among individuals. Some of these variability is
accounted for by genetic factors.
The present study was designed to evaluate the possibility that genetic polymorphism in the
gene encoding for mu opioid receptor may explain variability in the response to alfentanil
during lithotripsy.
Status | Completed |
Enrollment | 100 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 20 Years and older |
Eligibility |
Inclusion Criteria: - Age > 20 Exclusion Criteria: - Regular use of opioid drugs - Known hypersensitivity to alfentanil |
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Israel | Hadassah Medical Organization | Jerusalem |
Lead Sponsor | Collaborator |
---|---|
Hadassah Medical Organization |
Israel,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Total alfentanil dose used during the procedure. | |||
Primary | The extent of respiratory depression. |
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