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Nephrectomy clinical trials

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NCT ID: NCT01236326 Completed - Clinical trials for Kidney Transplantation

Conventional Laparoscopic Versus Laparoendoscopic Single Site Donor Nephrectomy in Living Donor Kidney Transplantation

Start date: November 2010
Phase: N/A
Study type: Interventional

Laparoscopic nephrectomy (removal of the kidney) is the most common procedure for people donating a kidney to be used for living donor kidney transplantation. Laparoscopic donor nephrectomy (LDN) was a great advance in the field of living donor kidney transplantation due to the many advantages it offers over open nephrectomy, including significantly shorter hospitalization and recovery time, and significantly improved cosmetic result related to the nephrectomy scar(s). More recently, a new procedure has been introduced to the field of laparoscopic nephrectomy, called laparoendoscopic single site donor nephrectomy (LESS-DN). In the LESS-DN procedure, a single natural orifice (the umbilicus or belly button) is used as the single incision site through which the entire donor nephrectomy is performed. The LESS-DN procedure may further decrease donor morbidity by further decreasing length of stay, lessening recovery time, and improving satisfaction with the surgical scar. The investigators propose to evaluate conventional LDN versus a LESS-DN in a randomized, controlled trial in living kidney donors. The investigators will compare operative times and intra-operative donor management, intra- and post-operative complications, pain scores, analgesic requirements, length of stay, recovery parameters, surgical scar satisfaction, and function and survival of the transplanted kidney for the two groups of subjects: (1) the group that has the conventional laparoscopic donor nephrectomy; and, (2) the group that has the laparoendoscopic single site donor nephrectomy.

NCT ID: NCT01235104 Active, not recruiting - Urolithiasis Clinical Trials

Impact of Total Nephrectomy on Patients With Kidney Stone

Start date: January 2001
Phase: N/A
Study type: Observational

The aim of this study is to investigate the outcomes of total nephrectomy on patients with kidney stone disease.

NCT ID: NCT01101490 Completed - Nephrectomy Clinical Trials

Changes of Right and Left Cerebral Oxygen Saturation and Blood Flow During Nephrectomy in Lateral Decubitus Position

Start date: April 2010
Phase: N/A
Study type: Observational

The purpose of this study is to determine changes of right and left cerebral oxygen saturation and blood flow during nephrectomy in lateral decubitus position.

NCT ID: NCT01093079 Recruiting - Tumor Clinical Trials

Laparoscopic Versus Open Partial Nephrectomy - Surgical and Oncological Outcomes

LapVsOpen prtn
Start date: September 2009
Phase: N/A
Study type: Observational

Partial Nephrectomy is the standard care for small (<4 cm) renal tumors. Despite the expanding use of laparoscopic approach, debate exist regarding the short and long term outcomes compared to the open approach. Our goal is to perform a prospective randomized trial to compare these methods

NCT ID: NCT01054469 Completed - Nephrectomy Clinical Trials

Transversus Abdominus Plane Block

Start date: March 2010
Phase: N/A
Study type: Interventional

Transversus Abdominus Plane (TAP) block may reduce need for postoperative pain medications in patients undergoing laparoscopic hand assisted nephrectomy. Our hypothesis is that the TAP block will result in a significant reduction in pain scores and morphine requirements in the active group.

NCT ID: NCT01008709 Terminated - Laparoscopy Clinical Trials

Comparison Study of Two Different Surgical Clips During Laparoscopic Urologic Surgery

Start date: October 2009
Phase: N/A
Study type: Interventional

Intracorporeal suturing and knot tying during robotic prostatectomy and laparoscopic and robotic renal surgery have historically been considered the most technically challenging and time consuming aspects of these procedures. With improved operative technique as well as the use of innovative surgical devices, vascular control during these surgeries is often less cumbersome as compared with traditional techniques. Current standard methods of hemostasis include the use of clips, of which the most popular design is the Hemolock, a locking, nonabsorbable plastic clip, or the use of the very expensive endomechanical stapler. Unfortunately while they are associated with time savings in the operating room, there is a great deal of disposable costs associated with these various devices as well as a not insignificant device malfunction rate reported in the literature. The aim of this case-controlled study is to evaluate the Aesculap U-clip device compared to our current technique of vascular control using the Teleflex Hemolock clip device during minimally invasive genitourinary surgery.

NCT ID: NCT00765232 Completed - Nephrectomy Clinical Trials

Intravenous Ketorolac for Postoperative Pain in Laparoscopic Donor Nephrectomy

Start date: October 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having laparoscopic surgery to donate a kidney.

NCT ID: NCT00598130 Completed - Nephrectomy Clinical Trials

Safety and Hemostatic Efficacy of Fibrin Fleece in Partial Nephrectomy

Fleece
Start date: February 2008
Phase: Phase 2
Study type: Interventional

This is a prospective, randomized, single blind, standard care- controlled study, which will include a total of 30 patients divided into two treatment arms: First are: patents who will be treated in accordance with standard of care. Second arm: patients for which the Fibrin Fleece will be applied directly on the active bleeding site.