Neoplasms Clinical Trial
Official title:
Integrative Parenteral Nutrition in Hospitalized, Malnourished, Hypophagic Cancer Patients With Contraindication to Enteral Nutrition
Although it is demonstrated that nutritional support can improve clinical outcomes, the
literature shows that approximately 50% of cancer patients are not able to meet their
estimated energy requirements. Recent clinical studies suggest that a supplementary support
for parenteral nutrition (PN) could significantly help to improve the nutritional status of
malnourished cancer patients.
International guidelines recommend the use of PN in malnourished, hypophagic, non-surgical
cancer patients if enteral nutrition is not feasible and in patients affected by severe
iatrogenic gastrointestinal complications and in whom inadequate food intake is anticipated
for more than 7 days. However, there are no studies on the effects of integrative PN in
hospitalized, malnourished, hypophagic, non-surgical cancer patients.
Recent studies have reported on the validity of bioelectrical impedance vector analysis in
monitoring the body composition of patients receiving nutritional support. Particularly,
phase angle proved to be a superior prognostic marker than other nutritional screening tools.
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