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Clinical Trial Summary

This Phase I clinical trial is studying the side effects and best dose of ABT-888 when given together with Whole Brain Radiation Therapy (WBRT) in treating patients with brain metastases.


Clinical Trial Description

This is a Phase 1, multicenter, dose-escalation study evaluating the safety, tolerability and pharmacokinetics of the PARP inhibitor ABT-888 in combination with conventional whole brain radiation therapy (WBRT) in the treatment of subjects with solid tumors metastatic to the brain. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00649207
Study type Interventional
Source AbbVie
Contact
Status Completed
Phase Phase 1
Start date March 2008
Completion date March 2013

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