Neonatal Hyperbilirubinemia Clinical Trial
Official title:
Bilicurves: Using Information Technology to Integrate Clinical Practice Guidelines Into the Management of Neonatal Hyperbilirubinemia
We will use information technology to integrate the 2004 American Academy of Pediatrics guidelines for management of neonatal hyperbilirubinemia with laboratory reporting of newborn bilirubin test results to improve physician adherence to the guidelines and quality of care.
In 2004, the American Academy of Pediatrics disseminated clinical practice guidelines for
the management of neonatal hyperbilirubinemia. Using the infant's age in hours, serum
bilirubin levels are applied to hour-specific nomograms to assess risk of developing
significant hyperbilirubinemia as well as the necessity for treatment. Prior guidelines did
not include nomograms for either. A systems approach to managing neonatal
hyperbilirubinemia, including use of the nomograms, has been shown to improve outcomes and
patient safety.
Despite the existence of these guidelines, decision support does not exist within MGH
clinical information systems for managing neonatal hyperbilirubinemia. We propose to create
BiliCurves, an application that integrates perinatal information from the obstetrical health
record with that of the newborn's, providing seamless reporting of neonatal bilirubin
results in the context of the practice guidelines and relevant obstetrical data. BiliCurves
will graphically superimpose bilirubin results onto hour-specific guideline nomograms that
providers can view when viewing bilirubin results. We propose to randomize BiliCurves access
to pediatric providers, and study its effects on management of hyperbilirubinemia both
during birth hospitalization as well as in the outpatient setting after discharge. We
hypothesize infants treated by physicians with BiliCurves access will receive birth
hospitalization phototherapy at a higher rate and readmission for hyperbilirubinemia at a
lower rate than that of the control group. We also hypothesize that physicians with
BiliCurves access will report greater ease and confidence in nomogram use and providing
evidence-based care as BiliCurves obviates the provider having to have access to paper based
versions of the nomogram (usual care) as well decreases potential errors in plotting test
results on the nomograms.
;
Observational Model: Cohort, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06186349 -
The Effect and Mechanism of Gene Variation on Neonatal Hyperbilirubinemia
|
||
Recruiting |
NCT04369313 -
Effect of DCC on Neonatal Jaundice and Blood Gas Analysis in Infants Born to GDM Mothers
|
N/A | |
Not yet recruiting |
NCT04585828 -
Comparison of Double Pad Fiber Optic Device Versus Conventional Phototherapy
|
N/A | |
Completed |
NCT02927093 -
Clinical and Developmental Outcomes of Babies Who Became Yellow in the First Month of Life
|
N/A | |
Unknown status |
NCT01340339 -
Reverse Phototherapy With Super Light-emitting Diode(Super-LED) for Hyperbilirubinemia in Term and Late Preterm Infants
|
Phase 4 | |
Completed |
NCT02033096 -
Observational Follow-up of Participants From Clinical Trial 64,185-202 (NCT00850993)
|
||
Recruiting |
NCT04218318 -
Safe Threshold to Discontinue Phototherapy in Hemolytic Disease of Newborn
|
N/A | |
Active, not recruiting |
NCT02602301 -
The Effect of Intravenous Oxytocin Infusion Using Different Diluents on Neonatal Bilirubin & Sodium Levels
|
Phase 4 | |
Active, not recruiting |
NCT05343403 -
Parental Participation on the Neonatal Ward - the neoPARTNER Study
|
||
Completed |
NCT03880591 -
Neonatal Hyperbilirubinaemia in the Democratic Republic of Congo
|
||
Completed |
NCT01599611 -
Follow-up of Extreme Neonatal Hyperbilirubinemia in 5-10 Year Old Children: a Danish Population Based Study
|
N/A | |
Recruiting |
NCT06399146 -
Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Population in Botswana
|
N/A | |
Completed |
NCT06018012 -
MRA and ABR as Early Predictors of Bilirubin-Induced Neurologic Dysfunction in Full-term Jaundiced Neonates
|
||
Completed |
NCT03536078 -
Home Phototherapy for Term Newborns With Icterus
|
N/A | |
Withdrawn |
NCT00917007 -
Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis
|
||
Recruiting |
NCT00154960 -
Establishing Novel Detection Techniques for Various Genetic-Related Diseases by Applying DHPLC Platform.
|
N/A | |
Recruiting |
NCT02594904 -
Efficacy of Yinzhihuang Oral Liquid on Indirect Bilirubin of Neonates With Glucose-6-phosphate Dehydrogenase Deficiency
|
Phase 4 | |
Completed |
NCT01746511 -
Glycerin Suppositories to Reduce Jaundice in Premature Infants
|
N/A | |
Completed |
NCT01470820 -
Dose-response Relationship of Phototherapy for Hyperbilirubinaemia Using Diodes: is There a "Saturation Point"
|
N/A | |
Completed |
NCT02361788 -
Study on Newborn Babies With a Yellow Skin Color (Neonatal Jaundice Study)
|