The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic

Needlestick Injuries Clinical Trial

Official title:

The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02086292
• Other study ID #: 2013/2297D
• Status: Completed
• Phase: N/A
• First received: March 11, 2014
• Last updated: September 15, 2016
• Start date: February 2014
• Est. completion date: June 2014

Study information

• Verified date: September 2016
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway:National Committee for Medical and Health Research Ethics
• Study type: Interventional

Clinical Trial Summary

The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection. It will be investigated whether a smaller volume of lidocaine can decrease pain during injection.

Description:

Healthy volunteers will receive a single subcutaneous injection digital nerve block at the base of each ring finger. 2ml 1% lidocaine in one of the fingers, and 1 ml 2% lidocaine in the other. After each injection, the subject will be asked to evaluate the pain on a visual analog scale (0-100 mm). Additionally the sensibility will be tested with a Semmes-Weinstein monofilament, to evaluate if the different methods achieve desired anesthetic effect.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 36
• Est. completion date: June 2014
• Est. primary completion date: June 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• age 18 - 65

Exclusion Criteria:

• regular use of analgesics

• known hypersensitivity of local anaesthetic

• renal-, heart- or liver disease

• known peripheral neuropathy or diabetes mellitus

• local infection on injection site

• circulation disorders in upper extremities (e.g. Raynaud´s phenomenon)

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Needlestick Injuries

Intervention

Procedure:
• 2 ml 1% Lidocaine

• 1 ml 2% Lidocaine

Locations

Country	Name	City	State
Norway	Department of neuroscience, NTNU	Trondheim

Sponsors (2)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology	St. Olavs Hospital

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Ballo S, Hjelseng T, Tangen LF, Lundbom JS, Skarsvåg T, Finsen V. The Influence of Injected Volume on Discomfort During Administration of Digital Block. J Hand Surg Asian Pac Vol. 2016 Oct;21(3):369-73. doi: 10.1142/S2424835516500363. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pain	visual analog scale 0-100mm; questionnaire	60 seconds	No