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Necrosis clinical trials

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NCT ID: NCT03753282 Withdrawn - Clinical trials for Avascular Necrosis of the Femoral Head

Outcome After Avascular Necrosis of the Femoral Head in Young Patients

AVN
Start date: January 30, 2019
Phase:
Study type: Observational

1. The course of AVN between Initial diagnosis and total hip replacement (THA) is analysed. The impact of early interventions versus conservative therapy in AVN before THA will be evaluated. 2. The short and long term outcomes of AVN patients undergoing THA with respect to complications, reoperations and quality of life are investigated. Potential risk factors for adverse outcomes will be investigated.

NCT ID: NCT03376984 Withdrawn - Clinical trials for Dental Pulp Necrosis

Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy

NDGX
Start date: June 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to to compare root canal therapy success between two root canal filler materials: 1) gutta percha (GP), 2) gutta percha modified with nanodiamonds and amoxicillin (NDGX). Gutta percha is the current standard root canal filler material used during non-surgical root canal therapy (RCT). Gutta percha modified with nanodiamonds and amoxicillin is an investigational root canal filler material, not yet FDA approved for use as described in this study. The safety and usefulness of NDGX is being tested in this study in comparison to the current standard of care, gutta percha (GP).

NCT ID: NCT02799654 Withdrawn - Hip Fractures Clinical Trials

Excia T Cementless EBRA Study

Start date: August 2017
Phase: N/A
Study type: Observational

In this Post Market Clinical Follow-up Study (PMCF Study), the short-term clinical and radiological results of the cementless Excia T® prosthesis in routine clinical use shall be assessed and the migration taking place in the first 24 months evaluated.

NCT ID: NCT02718092 Withdrawn - Walled-off Necrosis Clinical Trials

Comparing Fully Covered, Self Expanding Metal Stent (FCSEMS) and Plastic Stents for EUS- Guided Drainage of WON

WON
Start date: February 2016
Phase: N/A
Study type: Interventional

This is a multi-center, single-blinded, randomized trial comparing AXIOS FCSEMS (Fully Covered Self Expanding Metal Stent) and plastic stents for EUS (Endoscopic Ultrasound)-guided management of infected and/or symptomatic WON (Walled Off Necrosis). Patients will be randomized to either FCSEMS or plastic stents for EUS-guided drainage of WON in a 1:1 manner. Following EUS-guided drainage patients in both groups will be assessed pre- procedure, pre -discharge, weeks 1, 6 and months 3, 6, 12 and 24 months. Information will also be collected from any subsequent hospital admissions related to their walled-off necrosis.

NCT ID: NCT02564965 Withdrawn - Clinical trials for Necrotizing Pancreatitis

Endoscopic Large Caliber Drainage vs. Complete Necrosectomy for Treatment of Walled-off Pancreatic Necrosis

Start date: February 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to determine optimal treatment strategies for symptomatic walled-off pancreatic necrosis( WON).

NCT ID: NCT02342977 Withdrawn - Clinical trials for Rheumatoid Arthritis

Effects of Lacosamide on Post-operative Opioid Requirements After a Total Hip Arthroplasty:

Start date: November 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine how effect lacosamide is in reducing the amount of pain medication needed following a total hip arthroplasty. The study team hypothesizes that a single dose of lacosamide will reduce the amount of pain medication required after surgery. The study team plans to evaluate the amount of pain medication needed and quality of pain control during a subject's hospital stay and at their three month follow-up visit following their surgery.

NCT ID: NCT02273076 Withdrawn - Clinical trials for Disorders of Skin Grafts and Flaps

Predicting Breast Flap Necrosis by Spatial Frequency Domain Imaging

Start date: October 2014
Phase:
Study type: Observational

The current surgical procedure for breast diseases places an emphasis on the conservation of breast skin in order to provide more optimal reconstruction. The purpose of this study is to use portable, non-contact optical imaging device developed at the Beckman Laser Institute called Spatial Frequency Domain Imaging to detect the changes in a skin during reconstructive surgery procedure and healing process.

NCT ID: NCT01961934 Withdrawn - Gliomas Clinical Trials

C11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progression

Start date: May 2014
Phase: Phase 2/Phase 3
Study type: Interventional

This study will investigate how well Carbon Acetate PET/CT imaging helps to correctly identify recurrent tumor versus post treatment effects (radionecrosis) in patients with previously treated high grade brain gliomas.

NCT ID: NCT01462240 Withdrawn - Clinical trials for Rheumatoid Arthritis

LPS Flex Porous Femoral Components

Start date: May 20, 2008
Phase:
Study type: Observational

This is a prospective multicenter study of the LPS-Flex Porous Femoral Components when used in primary total knee arthroplasty. The purpose of the study is to obtain short-, mid-, and long-term clinical outcomes and implant survivorship data for the NexGen LPS-Flex Porous Femoral components.

NCT ID: NCT00699270 Withdrawn - Clinical trials for Rheumatoid Arthritis

A Clinical Investigation of the Comprehensive®, BioModular®, and Bi-Angular® Shoulder Systems

Start date: August 2007
Phase: N/A
Study type: Observational

The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of Biomet Humeral Stems