Neck Pain, Posterior Clinical Trial
— HVLATOfficial title:
The Effect of High-Velocity Low-Amplitude Thrust Manipulation of the Cervical Spine on Pain Biomarkers in Females With Non-Specific Mechanical Neck Pain
Verified date | July 2019 |
Source | Loma Linda University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study evaluates the effect of high-velocity low-amplitude thrust (HVLAT) manipulation to the cervical spine on neuropeptide expression as determined by the plasma concentration of oxytocin, neurotensin, orexin A and cortisol; and Examine the effect of HVLAT manipulation on pain perception in symptomatic females with non-specific mechanical cervical spine pain
Status | Completed |
Enrollment | 28 |
Est. completion date | September 20, 2016 |
Est. primary completion date | September 20, 2016 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 20 Years to 45 Years |
Eligibility |
Inclusion Criteria: - 20 - 45 years of age - A score of 10 or more out of 50 on the Neck Disability Index (NDI) questionnaire - Symptoms of pain present for 30 days or less and no pain symptoms below your shoulder Exclusion Criteria: - Serious condition (such as cancer, spondylolisthesis, rheumatoid arthritis, or ankylosing spondylitis) - Cervical spinal stenosis signs (such as incoordination in hands, arms and legs, inability of walking at a brisk pace, or bowel and bladder incontinence) - Nerve root compression (such as changes in sensation, muscle weakness, or decreased reflexes) - Works the night shift - Steroid medication within 3 months - Pregnancy or postpartum - Pending legal action regarding their neck pain - History of whiplash associated disorder and/or cervical spine surgery |
Country | Name | City | State |
---|---|---|---|
United States | Loma Linda University | Loma Linda | California |
Lead Sponsor | Collaborator |
---|---|
Loma Linda University |
United States,
Bronfort G, Haas M, Evans R, Leininger B, Triano J. Effectiveness of manual therapies: the UK evidence report. Chiropr Osteopat. 2010 Feb 25;18:3. doi: 10.1186/1746-1340-18-3. — View Citation
Gross A, Miller J, D'Sylva J, Burnie SJ, Goldsmith CH, Graham N, Haines T, Brønfort G, Hoving JL; COG. Manipulation or mobilisation for neck pain: a Cochrane Review. Man Ther. 2010 Aug;15(4):315-33. doi: 10.1016/j.math.2010.04.002. Epub 2010 May 26. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Plasma Concentration of Oxytocin | Samples were analyzed for Human Oxytocin, using the Multiplex Luminex-100 platform (Luminex, Inc., USA). | Blood will be drawn 10 minutes prior to HVLAT procedure. | |
Primary | Plasma Concentration of Oxytocin | Samples were analyzed for Human Oxytocin, using the Multiplex Luminex-100 platform (Luminex, Inc., USA). | Blood will be drawn immediately after HVLAT procedure. | |
Secondary | Plasma Concentration of Neurotensin | Samples were analyzed for Human Neurotensin, using the Multiplex Luminex-100 platform (Luminex, Inc., USA). | Within 10 minutes after consent signature completion | |
Secondary | Plasma Concentration of Neurotensin | Samples were analyzed for Human Neurotensin, using the Multiplex Luminex-100 platform (Luminex, Inc., USA). | Blood will be drawn immediately after HVLAT procedure. | |
Secondary | Plasma Concentration of Orexin A | Samples were analyzed for Human Orexin A, using the Multiplex Luminex-100 platform (Luminex, Inc., USA). | Within 10 minutes after consent signature completion | |
Secondary | Plasma Concentration of Orexin A | Samples were analyzed for Human Orexin A, using the Multiplex Luminex-100 platform (Luminex, Inc., USA). | Blood will be drawn immediately after HVLAT procedure. | |
Secondary | Plasma Concentration of Cortisol | Samples were analyzed for Human Cortisol, using the Multiplex Luminex-100 platform (Luminex, Inc., USA). | Within 10 minutes after consent signature completion | |
Secondary | Plasma Concentration of Cortisol | Samples were analyzed for Human Cortisol, using the Multiplex Luminex-100 platform (Luminex, Inc., USA). | Blood will be drawn immediately after HVLAT procedure. |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05617365 -
Treating Chronic Cervicogenic Head and Neck Pain
|
Phase 1/Phase 2 | |
Recruiting |
NCT05607459 -
Dry Needling, Manual Therapy and Exercise for Neck Pain Management
|
N/A | |
Completed |
NCT04256031 -
Effects of Smartphone Use on Posture, Pain, Function and QoL
|
||
Recruiting |
NCT05074381 -
Dry Needling of the M. Obliquus Capitis Inferior on Rotational Mobility and Headache Related Outcome Measures in CH.
|
N/A | |
Completed |
NCT04113824 -
The Efficacy and Safety of Trapezius MSAT on Acute Whiplash Injury
|
N/A | |
Not yet recruiting |
NCT05428254 -
Radiofrequency Therapy for Chronic Neck Pain.
|
N/A | |
Recruiting |
NCT05605132 -
SENSORY RE-TRAINING IN PATIENTS WITH CHRONIC NECK PAIN
|
N/A | |
Completed |
NCT05111704 -
Short-term Effects of Postural Taping on Pain and Neck Posture
|
N/A | |
Completed |
NCT04378959 -
Lidocaine Patch for Neck Pain
|
N/A | |
Completed |
NCT04725825 -
Central Pain Modulatory Effects of Dry-Needling in Patients With Non-Specific Neck Pain
|
N/A | |
Completed |
NCT03241134 -
Changes in Surface EMG Activity After Dry Needling Compared to Sham Needling
|
N/A | |
Completed |
NCT05524623 -
Comparative Effect of MEP With or Without Current Emission in the Treatment of Cervical Pain in MTrPs of the Trapezius
|
N/A | |
Withdrawn |
NCT03859011 -
Acupuncture Relief for Chronic Neck Pain
|
N/A | |
Completed |
NCT03495076 -
Perceptual Distortions in Acute Neck Pain
|
N/A |