Nasopharyngeal Carcinoma Clinical Trial
Official title:
Adjuvant Chemotherapy or Not for NPC Patients Staged N2-3M0 After Concurrent Chemotherapy :a Phase Ⅱ Study
By this clinical trial, the investigators are trying to give an answer to such a question. Whether NPC patients staged N2-3M0 need adjuvant chemotherapy consisting of paclitaxel and platinum after concurrent chemoradiation?
Status | Terminated |
Enrollment | 10 |
Est. completion date | October 2015 |
Est. primary completion date | September 2015 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 65 Years |
Eligibility |
Inclusion Criteria: 1. pathologically confirmed untreated NPC patients staged N2-3M0 2. age: 18y - 65y 3. with MRI examinations 4. ECOG=2 5. with written consent Exclusion Criteria: 1. without a second cancer 2. pregnancy 3. with other severe diseases(blood,liver ,kidney or heart diseases) 4. could not staged properly 5. without written consent |
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
China | Jiangsu Cancer Hospital | Nanjing | Jiangsu |
Lead Sponsor | Collaborator |
---|---|
Jiangsu Cancer Institute & Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | distant metastasis free survival | 24 months | No | |
Primary | treatment toxicity based on a CTCAE3.0 grading system | 6 months | Yes | |
Secondary | progress free survival | 24 months | No |
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