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Elimination of Adjuvant Chemotherapy for Selected Stage II and III Nasopharyngeal Carcinoma

Nasopharyngeal Cancer Clinical Trial

Official title:
Elimination of Adjuvant Chemotherapy for Selected Stage II and III Nasopharyngeal Carcinoma After Concomitant Radiotherapy And Chemotherapy

Clinical Trial Summary

This study evaluates whether some patients with nasopharyngeal carcinoma but with low risk of distant metastasis can be treated with only radiotherapy and concomitant chemotherapy but without additional adjuvant chemotherapy.

Clinical Trial Description

The standard treatment for stage II-III nasopharyngeal carcinoma is radiotherapy with concomitant chemotherapy and adjuvant chemotherapy. A subset of these patients has very low risk for distant metastasis that adjuvant chemotherapy is probably unnecessary. The investigators would like to know if same therapeutic effect and survival rate can be achieved without adjuvant chemotherapy, (i.e. less chemotherapy, same effect) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03175939
Study type Interventional
Source Sun Yat-sen University
Contact
Status Completed
Phase Phase 2
Start date April 1, 1998
Completion date December 31, 2014
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