Clinical Trials Logo

Nasolacrimal Duct Obstruction clinical trials

View clinical trials related to Nasolacrimal Duct Obstruction.

Filter by:
  • Completed  
  • Page 1

NCT ID: NCT01766232 Completed - Epiphora Clinical Trials

Lacrimal Drainage Resistance Study

LDRS
Start date: April 2009
Phase: N/A
Study type: Observational

Epiphora, or uncontrolled tearing of the eyes, represents a common presenting complaint of patients seen by ophthalmologists. Epiphora may be due to non-obstructive causes, such as tear hypersecretion or functional tear pump failure, or obstructive causes. Functional tear pump failure may result from malposition of the eyelids, such as an abnormal out-turning (ectropion) or in-turning (entropion) of the eyelid. Currently methods to diagnose partial nasolacrimal duct obstruction are purely qualitative in nature. Our research goal is to quantitatively measure the pressure generated during conventional probing and irrigation (P&I), and to measure the resistance to irrigation of the nasolacrimal drainage system. The investigators will measure the pressure generated during conventional P&I using a disposable in-line pressure transducer. In addition, the investigators will use a syringe pump to deliver a constant flow rate of saline through a nasolacrimal cannula and measure the steady state irrigation pressure using the in-line transducer and digital pressure monitor. Resistance can be directly calculated from the known flow rate and pressure measurements. The investigators will compare both the pressure generated during P&I and the lacrimal drainage resistance between patients with lacrimal drainage obstruction and controls patients with no obstruction (functional tear pump failure) as determined by clinical exam. Clinical applications for measuring lacrimal drainage resistance include quantifying partial nasolacrimal duct obstruction, guiding the choice of surgical procedure, and determining the success of lacrimal drainage procedures.

NCT ID: NCT01233596 Completed - Clinical trials for Nasolacrimal Duct Obstruction

Monocanalicular Versus Bicanalicular Intubation in the Treatment of Congenital Nasolacrimal Duct Obstruction

MCI_vs_BCI
Start date: January 2006
Phase: Phase 3
Study type: Interventional

The aim of the study was to compare the success rate of monocanalicular intubation versus bicanalicular silicone intubation in congenital nasolacrimal duct obstruction in children aged between 10 and 36 months.

NCT ID: NCT00784992 Completed - Clinical trials for Nasolacrimal Duct Obstruction

A Comparison of Endonasal Dacryocystorhinostomy With and Without Silicone Tubes

Start date: November 2008
Phase: Phase 4
Study type: Interventional

Aim of study is to investigate whether the use of silicone tubes in endonasal DCR surgery increases the success rate and / or complication rate compared to surgery without tubes.

NCT ID: NCT00780741 Completed - Clinical trials for Nasolacrimal Duct Obstruction

Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old

NLD3
Start date: October 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is: To determine the cost-effectiveness of treating NLDO using immediate office probing compared with deferred probing in a facility setting. As part of the primary objective, the study will determine the proportion of eyes experiencing spontaneous resolution among subjects randomized to the deferred probing group. The secondary objectives are: 1. To determine the success proportion for eyes undergoing immediate office probing as an initial procedure. 2. To determine the success proportion for eyes undergoing deferred facility probing as an initial procedure.

NCT ID: NCT00315315 Completed - Clinical trials for Nasolacrimal Duct Obstruction

Study of Surgical Procedures for Treatment of Persistent Nasolacrimal Duct Obstruction in Children < 4 Years Old

NLD2
Start date: February 2005
Phase: Phase 3
Study type: Observational

The purpose of this study is: - To report the success proportions for the treatment of persistent nasolacrimal duct obstruction for three surgical procedures: balloon catheter dilation, nasolacrimal intubation, and simple probing. - To obtain descriptive data regarding symptoms and quality of life in patients receiving each type of surgical procedure, and to compare success proportions between patients undergoing balloon catheter dilation and those undergoing nasolacrimal intubation.

NCT ID: NCT00315289 Completed - Clinical trials for Nasolacrimal Duct Obstruction

Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years Old

NLD1
Start date: February 2005
Phase: Phase 3
Study type: Observational

The purpose of this study is: - To report the success proportions of simple probing within different age groups of patients under 24 months of age. - To obtain descriptive data regarding symptoms and quality of life in patients receiving simple probing. - To obtain similar data for simple probing in patients 24 months of age or older, for intubation in patients age 6 - <48 months, and for balloon catheter dilation in patients age 6 - <48 months.