Clinical Trials Logo

Clinical Trial Summary

Managing pain in postoperative patients presents challenges in striking a balance between achieving adequate pain control and over-prescribing opioids that have the potential to contribute to the opioid epidemic. There are no clear guidelines informing postoperative opioid prescribing in obstetrics and gynecology.

The primary aim for this study are to better understand the factors that impact opioid use for pain management in gynecologic surgery patient after discharge. The second aim is to develop a model that incorporates individual patient baseline measures (e.g. anxiety, fibromyalgia score, inpatient narcotic consumption) to predict the amount of opioids needed following discharge.


Clinical Trial Description

Managing pain in postoperative patients presents challenges in striking a balance between achieving adequate pain control and over-prescribing opioids that have the potential to contribute to the opioid epidemic. There are no clear guidelines informing postoperative opioid prescribing in obstetrics and gynecology. A recent study by As-Sanie et al. demonstrated that gynecologists at a large academic medical center prescribe twice the amount of opioids than the average patient uses after hysterectomy.1 Similarly, a study completed at Vanderbilt University Medical Center showed that obstetricians were overprescribing narcotics to patients after cesarean deliveries.2

In addition to rates of opioid prescribing, other factors affect postoperative opioid consumption, including individual patient measures of anxiety, depression, and self-reported pain scores prior to surgery. Preoperative Fibromyalgia symptom scores, STAIT state anxiety scores and NRS pain expectations are independent predictors for morphine consumption following hysterectomy.

There is a pressing need to better understand the factors that impact opioid use in women who undergo gynecologic surgery in order to mitigate the over-use of opioids for pain control upon discharge from the hospital.

Aims:

1. Understand the factors that impact opioid use for pain management in gynecologic surgery patients after discharge.

1. Is opioid consumption during the immediate postoperative recovery phase associated with consumption after discharge?

2. Are variables that are known to be associated with opioid consumption, also associated with opioid consumption after discharge?

3. Are there factors which we can use to predict opioid consumption in postoperative patients?

2. Develop a model that incorporates individual patient baseline measures (e.g. anxiety, fibromyalgia score, inpatient narcotic consumption) to predict the amount of opioids needed following discharge. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03728517
Study type Observational
Source Indiana University
Contact
Status Terminated
Phase
Start date August 23, 2018
Completion date January 1, 2019

See also
  Status Clinical Trial Phase
Recruiting NCT04130464 - Intraperitoneal Infusion of Analgesic for Postoperative Pain Management Phase 4
Terminated NCT03330119 - Determining the Effect of an "Alternate Recovery Protocol" Versus Current Standard of Care After Cesarean Section Phase 3
Completed NCT05592522 - Efficacy of External Oblique Intercostal Block in Laparoscopic Bariatric Surgery N/A
Withdrawn NCT03197311 - A Mobile Application for Post-op Analgesic Consumption N/A
Completed NCT03422211 - A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries
Not yet recruiting NCT05611749 - Duloxetine Impact on Postoperative Pain Control and Outcomes Phase 2
Terminated NCT06458842 - Postoperative Pain Protocol Limiting Narcotics for Laparoscopic Hand-assisted Donor Nephrectomy N/A
Recruiting NCT04791943 - Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery Phase 2
Not yet recruiting NCT04305730 - Use of Pedometer Following Radical Cystectomy N/A
Completed NCT02110719 - Decreasing Narcotics in Advanced Pelvic Surgery Phase 4
Completed NCT05758090 - Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years N/A
Completed NCT04710069 - Postoperative Opt-In Narcotic Treatment Study N/A
Completed NCT04019834 - Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy Early Phase 1
Completed NCT04362566 - Bupivacaine for Post-operative Pain in Mohs Phase 4
Recruiting NCT03825809 - Nonopioid Analgesia After Labral Surgery Phase 2/Phase 3
Completed NCT03820193 - Nonopioid Analgesia After Arthroscopic Meniscus Surgery Early Phase 1
Withdrawn NCT04444830 - Sprix for Postoperative Pain Control Following Gynecologic Surgery Phase 4
Completed NCT03341533 - Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy N/A
Recruiting NCT05463367 - Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure Phase 2
Terminated NCT03682367 - Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery Phase 3