Nail Abnormalities Clinical Trial
Official title:
Pilot Study of Efficacy of Nail Gel Containing Artemisia Abrotanum Extract and Glycerin in Finger Nail Surface Abnormality
Nail surface abnormalities is any conditions that affect the nail matrix or nail bed which
cause nail plates grow defectively. Common nail surface abnormalities are pitting nails,
longitudinal ridging, and transverse ridging/Beau's line. Aging nails usually have nail
surface abnormalities as well.
Nail gels are artificial nails used widely for aesthetic purposes. Although, their cosmetic
use is increasing with day by day, their usefulness in conditions such as nail biting,
brittle nails, and ingrown toe nails has been reported. Moreover, a previous study reported
the benefits of nail gels in terms of improving nail surface abnormalities like pitting
nails, trachyonychia, and onychoschizia.
This study was conducted to evaluate the efficacy of nail gel containing Glycerin which has
humectant effect and Artemisia Abrotanum extract which has anti-fungal/bacterial activities
in finger nail surface abnormalities.
Evaluation of nail surface abnormality can be done by using Visiometer® (bioengineering
measurement) and dermoscope. Both techniques are non-invasive.
Artemisia Abrotanum extract has been used as ingredient in cosmetic products and its safety
has been declared. Undesirable events from external using products containing this substance
have never been reported yet. Nail gel product in this study has been approved as a cosmetic
product by Food and Drug Administration of Thailand (Thai FDA).
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Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment