NAFLD Clinical Trial - Response of NAFLD Patients to Mediterranean Diet

Status Completed

Clinical Trial Summary

The effects of Mediterranean Diet (MedDiet) on clinical, biochemical and inflammatory profile in NAFLD patients with simple steatosis. Potential associations of single nucleotide polymorphisms to diet composition and patients' profile were also investigated.

Clinical Trial Description

Diet is a modifiable key factor targeted in prevention and management of non-alcoholic fatty liver disease (NAFLD). The aim of the study is to investigate the effect of Mediterranean Diet (MedDiet) on clinical, biochemical and inflammatory profile in NAFLD patients with simple steatosis. Potential associations of single nucleotide polymorphisms to diet composition and patients' profile are investigated. In this non-randomised, open-label study, 44 untreated NAFLD patients with non significant fibrosis receive nutritional counsel to increase adherence to MedDiet. Adherence to MedDiet is estimated with MedDietScore. Furthermore, genotyping of STAT3 rs2293152 and GCKR rs1260326 single nucleotide polymorphisms takes place. ;

Study Design

Related Conditions & MeSH terms

Fatty Liver
NAFLD
Non-alcoholic Fatty Liver Disease
Steatosis of Liver

Clinical Trial Details

NCT number	NCT03203486
Study type	Interventional
Source	Harokopio University
Contact
Status	Completed
Phase	N/A
Start date	April 2014
Completion date	October 2014

View Details

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