Clinical Trials Logo
  1. Home
  2. Myotonic Dystrophy
  3. NCT00233519

Effects of SomatoKine (Iplex)Recombinant Human Insulin-like Growth Factor-1/Recombinant Human Insulin-like Growth Factor-binding Protein-3 (rhIGF-I/rhIGFBP-3) in Myotonic Dystrophy Type 1 (DM1)

Myotonic Dystrophy Clinical Trial

Official title:
Effects of SomatoKine (Iplex) (rhIGF-I/rhIGFBP-3) in Myotonic Dystrophy Type 1 (DM1)

Clinical Trial Summary

The aim of this study is to investigate the safety and feasibility of daily subcutaneous injections of recombinant IGF1 complexed with IGF binding protein 3 (SomatoKine-INSMED) as a treatment for muscle wasting and weakness in myotonic dystrophy type 1.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00233519
Study type Interventional
Source University of Rochester
Contact
Status Completed
Phase Phase 1/Phase 2
Start date November 2005
Completion date May 2008
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04624750 - Open Label Study in Adolescents and Children With Myotonic Disorders Phase 3
Recruiting NCT00082108 - Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry
Recruiting NCT05890833 - The Risk of Falls Index for Patients With Neuromuscular Disorders
Completed NCT05027269 - Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients Phase 1/Phase 2
Completed NCT00167609 - Efficacy and Safety of DHEA for Myotonic Dystrophy Phase 2/Phase 3
Recruiting NCT06411288 - Global Study of Del-desiran for the Treatment of DM1 Phase 3
Recruiting NCT04003363 - The United Kingdom National Registry for Myotonic Dystrophy
Completed NCT01136330 - DM1 Heart Registry - DM1 Respiratory Registry N/A
Completed NCT02375087 - Sleep Breathing Disorders, a Main Trigger for Cardiac ARythmias in Type I Myotonic Dystrophy ?
Completed NCT01406873 - Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1 Phase 2
Completed NCT03959189 - Safety, Tolerability and Pharmacokinetics of ERX-963 in Adults With Myotonic Dystrophy Type 1 Phase 1
Completed NCT01931644 - At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
Recruiting NCT00127582 - RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy Phase 3
Recruiting NCT02398786 - Myotonic Dystrophy Family Registry
Recruiting NCT05019625 - Biomarker Development for Muscular Dystrophies
Recruiting NCT05020002 - Extracellular RNA Biomarkers of Myotonic Dystrophy
Active, not recruiting NCT04616807 - An Observational Study in Adult Patients With Non-dystrophic Myotonic Disorders
Active, not recruiting NCT05479981 - Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients Phase 2
Terminated NCT02315339 - European Home Mechanical Ventilation Registry
Not yet recruiting NCT06147414 - Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders