Prevalence and Environmental Factors for Myopia Among Chinese School-aged Children and Adolescent in Tianjin

Myopia Clinical Trial

Official title:

Prevalence and Environmental Factors for Myopia Among Chinese School-aged Children and Adolescent in Tianjin

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05336799
• Other study ID #: Tianjin Myopia Study
• Status: Recruiting
• Start date: March 1, 2021
• Est. completion date: December 31, 2025

Study information

• Verified date: November 2022
• Source: Tianjin Eye Hospital
• Contact: xiaoyan yang, director
• Phone: +8627306525
• Email: yanzitjsykyy[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The high prevalence of myopia has become a global public health problem. The study amied to investigate the prevalence and progression of myopia associated with social environmental factors in Tianjin, a Chinese megacity in north China.

Description:

The high prevalence of myopia has become a global public health problem, especially in East and South Asian countries. It's still not clear for the prevalence and progression of myopia associated with social environmental factors. Thus, the investigators will conducted a long-term observational study to the effect of the socioeconomics, medical resources and school-related environmental parameters and others on the prevalence and progression of myopia among Chinese school-aged children and adolescent.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 500000
• Est. completion date: December 31, 2025
• Est. primary completion date: December 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 6 Years to 18 Years

Eligibility

Inclusion Criteria:

• aged 6 to 18 years

• no ocular diseases and systemic diseases

• consent to undergo an eye examination

Exclusion Criteria:

• schoolchildren unwilling to participate

Related Conditions & MeSH terms

• Myopia
• Refractive Errors

Locations

Country	Name	City	State
China	Tianjin Eye Hospital	Tianjin	Tianjin

Sponsors (1)

Lead Sponsor	Collaborator
Tianjin Eye Hospital

Country where clinical trial is conducted

China, 

References & Publications (3)

Guo Y, Liu LJ, Xu L, Lv YY, Tang P, Feng Y, Meng M, Jonas JB. Outdoor activity and myopia among primary students in rural and urban regions of Beijing. Ophthalmology. 2013 Feb;120(2):277-83. doi: 10.1016/j.ophtha.2012.07.086. Epub 2012 Oct 23. — View Citation

Morgan IG, French AN, Ashby RS, Guo X, Ding X, He M, Rose KA. The epidemics of myopia: Aetiology and prevention. Prog Retin Eye Res. 2018 Jan;62:134-149. doi: 10.1016/j.preteyeres.2017.09.004. Epub 2017 Sep 23. Review. — View Citation

Tenovuo J, Mielityinen H, Paunio K. The effect of dental plaque grown in the presence of xylitol or sucrose on bone resorption in vitro. Pharmacol Ther Dent. 1981;6(1-2):35-43. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of myopia	Myopia is defined as any eye's SER (sphere + 1/2 cylinder) of at least -0.5 diopters (D).	up to 3years
Secondary	Changes in prevalence of myopia	Myopia is defined as any eye's SER (sphere + 1/2 cylinder) of at least -0.5 diopters (D).	up to 3years
Secondary	Changes of Spherical equivalent	Changes of Spherical equivalent	changes from baseline at 36months