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Myopia, Progressive clinical trials

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NCT ID: NCT05372991 Completed - Myopia, Progressive Clinical Trials

Safety, Tolerability and Pharmacodynamics Evaluation of CBT-009 Eye Drop

Start date: July 20, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Two-Stage Phase 1/2 study to evaluate the safety, tolerability and pharmacodynamics of CBT-009 eye drop in healthy volunteers. CBT-009 has the active ingredient of atropine, which at low doses, has shown to be effective in slowing down myopic deterioration. Current atropine products are prone to degradation once the container is open to the air. ADS Pharmaceutical has developed a novel atropine formulation.

NCT ID: NCT05331378 Active, not recruiting - Myopia Clinical Trials

Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression

Start date: April 25, 2022
Phase: N/A
Study type: Interventional

This is a monocenter, randomized, controlled, parallel-group, double-masked clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation at baseline compared to a single vision spectacle lens (control). A total of 80 children will be recruited where 40 subjects will be allocated either to wear test lenses (group 1) or control lenses (group 2) for 1 year through randomization.

NCT ID: NCT05300321 Completed - Myopia, Progressive Clinical Trials

DIMS-myopia Progression ADN Axial Length Growth

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective randomized controlled clinical study.

NCT ID: NCT05007626 Completed - Myopia, Progressive Clinical Trials

Near Horizontal Heterophoria in Chinese Children

Start date: January 29, 2017
Phase:
Study type: Observational

This study aimed to assess the association of refraction and axial length with near-horizontal heterophoria in a large population-based study of school-aged Chinese children. The study makes a significant contribution to better know the etiology of myopia progression and ocular axial length development. Further, this study will be of interest to the readership of your journal because its noteworthy finding and which could contribute to guide recommendations for targeted interventions to slow myopia progression.

NCT ID: NCT04806763 Completed - Children, Only Clinical Trials

Myopia Control With Orthokeratology Contact Lenses in Spain

MCOS
Start date: March 1, 2007
Phase: N/A
Study type: Interventional

The purpose of this prospective study is to assess the efficacy, safety and patient-reported outcomes of the Menicon Z Night orthokeratolgy contact lens for reducing myopia progression in children.

NCT ID: NCT04806711 Completed - Children, Only Clinical Trials

Eleven Years of Menicon Z Night Contact Lens Wear in Reducing Myopia Progression in Children

MCOS11
Start date: March 1, 2007
Phase: N/A
Study type: Interventional

To compare axial length growth of white European myopic children wearing Menicon Z Night orthokeratology contact lenses to a control group of distance, single-vision glasses and contact lenses over an 11-year period.

NCT ID: NCT04806698 Completed - Children, Only Clinical Trials

Long-term Efficacy of Orthokeratology Contact Lens Wear in Controlling the Progression of Childhood Myopia

MCOS7
Start date: March 1, 2007
Phase: N/A
Study type: Interventional

To assess the long-term efficacy of the Menicon Z Night orthokeratology contact lens in controlling the progression of childhood myopia

NCT ID: NCT04770610 Active, not recruiting - Myopia, Progressive Clinical Trials

Study of OT-101 in Treating Myopia

Start date: April 1, 2021
Phase: Phase 3
Study type: Interventional

This is a phase III, randomized, double-masked, placebo-controlled, parallel-group, multicenter safety, tolerability, and efficacy study of atropine sulfate 0.01% (OT-101) as an investigational treatment for myopia in pediatric subjects

NCT ID: NCT04722874 Recruiting - Eye Diseases Clinical Trials

Repeated Low-Level Red-Light Therapy and Orthokeratology in Fast-progressing Myopia Control

Start date: March 14, 2021
Phase: N/A
Study type: Interventional

The purpose of this multicenter randomized clinical trial is to evaluate the adjunctive effect of repeated low-level red-light therapy (RLRL) and orthokeratology (ortho-k) on myopia control in ortho-k non-responders who have undergone ortho-k treatment but were still experiencing fast myopia progression.

NCT ID: NCT04334369 Withdrawn - Myopia, Progressive Clinical Trials

Contact Lens and Myopia Control in Optometry School Students

Start date: December 12, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the effect of Natural View Multifocal lenses, a soft multifocal lens, on retardation of myopia in an optometric student population. Close up work (i.e. reading, computer work, etc.) is thought to play a factor in the progression of myopia in young adults. The progression should be slowed if not stopped through the use of peripheral defocus lenses (Natural View Multifocal) to change the optics of the eye in order to focus the image on the peripheral retina as opposed to behind it.