Clinical Trials Logo
  1. Home
  2. Myoma
  3. NCT04694677
  4. Details
NCT04694677 Clinical Trial

Safety of Tranexamic Acid in Reducing Blood Loss Myomectomy.

Myoma Clinical Trial

Official title:
Safety of Tranexamic Acid Versus Misoprostol in Reducing Blood Loss in Myomectomy.

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT04694677
Other study ID # Myomectomy
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date January 10, 2021
Est. completion date September 10, 2021

Study information
Verified date January 2021
Source Aljazeera Hospital
Contact Mahmoud Alalfy
Phone 01002611058
Email mahmoudalalfy@ymail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Uterine leiomyomas (fibroids) are the most common benign tumors among women . Fibroids are found in approximately 15% to 30% of women in the reproductive age group

Description:

Although most of them are asymptomatic, 20-50% of fibroids may cause problems such as heavy menstrual bleeding, anemia, pelvic pain, pressure symptoms from extrinsic compression of the colorectal and urinary tract, infertility, and recurrent pregnancy losses, where surgical intervention is often indicated

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 60
Est. completion date September 10, 2021
Est. primary completion date August 15, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 20 Years to 50 Years
Eligibility Inclusion Criteria: - women with myomas Exclusion Criteria: - with with malignant lesions

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• women receiving tranexamic acid
women receiving tranexamic acid during myomectomy
• women receiving misoprostol
women receiving misoprostol in myomectomy

Locations
Country Name City State
Egypt Algazeerah Giza

Sponsors (2)
Lead Sponsor Collaborator
Aljazeera Hospital Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary the number of women who will have less blood loss how many women will have less blood loss 48 hours
See also
  Status Clinical Trial Phase
Completed NCT00528177 - Morphine vs. Oxycodone for Postoperative Pain Management Phase 4
Completed NCT05925153 - Vision Screening Study for College Students at Nankai University
Completed NCT02737553 - Laparoscopic Enclosed Morcellation; Electromechanic Morcellation vs Vaginal Removal N/A
Completed NCT00891657 - Post Market Study for an Adhesion Barrier Following Laparoscopic Myomectomy N/A
Completed NCT03972917 - Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy
Completed NCT02747550 - Temporary Simultaneous Two-arterial Occlusions During Laparoscopic Myomectomy N/A
Completed NCT00898170 - Effect of Myoma Removal on Blood Pressure and Erythropoetin Level N/A
Withdrawn NCT02377492 - Paracervical Vasopressin Injection Compared With Intramyometrial Vasopressin in Abdominal Myomectomy N/A
Recruiting NCT05806307 - Methods Decreasing Bleeding in Open Myomectomy Phase 4
Recruiting NCT00351494 - Myoma Microvascularization Analysis Using Sonovue Before and After Uterine Artery Embolization N/A
Completed NCT00562471 - Safety and Efficacy Study of a Hydrogel, Applied Following Removal of Myomas During Gynecologic Surgery, Administered for the Prevention/Reduction of Postoperative Adhesion Formation Phase 1/Phase 2
Recruiting NCT01564602 - To Compare to 2-channel and Multiple-channel Single Port Laparoscopic-assisted Vaginal Hysterectomy N/A
Completed NCT01032213 - Effect of Magnesium Sulphate on Coagulation N/A
Completed NCT03427671 - OCL 500 Treatment of Women With Symptomatic Uterine Fibroids N/A
Completed NCT04983719 - Transcervical Myoma Biopsy Video
Recruiting NCT05170230 - The Effect of Intracapsular Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomectomy Operations N/A
Recruiting NCT05683041 - Prevention of Intra-uterine Adhesions Following Laparoscopic and Laparotomic Myomectomy N/A
Recruiting NCT05242783 - The Effect of Intramyometrial Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Open Myomectomy Operations Using Haemostatic Tourniquets: N/A
Recruiting NCT05266534 - The Effect of Intramyometrial Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Open Myomectomy Operations Without Using Haemostatic Tourniquets N/A
Completed NCT02853695 - Implementation of Hysteroscopy in Flanders and the Netherlands