Myofascial Pain Clinical Trial
Official title:
Magnetic Resonance Elastography of Myofascial Pain Syndrome
Verified date | May 2024 |
Source | Mayo Clinic |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this research study is to use a new imaging technique called Magnetic Resonance (MR) Elastography to create new imaging parameters to measure the mechanical properties of myofascial tissues that can be used to assess the impaired myofascial interface in myofascial pain syndrome (MPS).
Status | Enrolling by invitation |
Enrollment | 106 |
Est. completion date | August 2025 |
Est. primary completion date | August 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Healthy Volunteer Inclusion Criteria: - Absence of a history of chronic pain in the targeted anatomical location (i.e., lower back and low extremities) that had limited activities of daily living or work - A numerical current pain index of less than 0.5 (on a 10-point Visual Analog Scale) - Able to understand the goal of the project and give informed consent. Healthy Volunteer Exclusion Criteria: - Pregnancy or breastfeeding - Any contraindication to an MRI exam - Previous severe/acute back or low extremity injury (including fracture) - Previous back or low extremity surgery - Back and lower limb deformities - Inability to provide consent. Myofascial-Related Pain Patient Inclusion Criteria: - A history of chronic low back or leg pain (the targeted location will be determined based on the findings in Aim 1) for at least 3 months. (Measured by patient history and physical exam) - A palpable taut band or nodule within the skeletal muscle - Hypersensitive tender spot within the taut band - Recognition of current pain complaint by pressure on the tender nodule/taut band - Painful limit to the full stretch range of motion Myofascial-Related Pain Patient Exclusion Criteria: - Pregnancy or breastfeeding - Any contraindication to an MRI exam - Previous therapy in the area to be treated within 6 months - Previous severe back or low extremity injury (including fracture) or surgery - Any neurological conditions or active systemic disease (e.g. diabetes, peripheral vascular disease, cancer, rheumatoid arthritis) that impaired sensation/pain perception - Severe osteoarthritis - Skin injuries in the area to be treated - Inability to provide consent. |
Country | Name | City | State |
---|---|---|---|
United States | Mayo Clinic Minnesota | Rochester | Minnesota |
Lead Sponsor | Collaborator |
---|---|
Mayo Clinic | National Center for Complementary and Integrative Health (NCCIH) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The fascia plane mobility assessed by MR Elastography-based normalized octahedral shear strain (NOSS) measurements | In response to an external shear force, the fascial layers that surround and separate muscles can deform or slide relative to each other, depending on the fascial plane's mobility. An adhesive interface that experiences a shear force will exhibit shear displacement continuity (i.e., small shear strain) across the interface, while a nonadhesive interface may slip rather than deform, which causes a discontinuity in displacement (i.e., large shear strain). For the targeted fascia plane in low back and legs, the normalized octahedral shear strain (NOSS) will be computed from the shear displacement data measured from MRE to assess the fascia plane mobility. The primary outcome measure is the difference in the fascia plane mobility on MR elastography between patients with myofascial-related pain diseases and healthy controls without myofascial-related pain diseases. | baseline measures through the study completion (3 years) |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04157426 -
Percutaneous Electrolysis Versus Dry Needling in Levator Scapulae
|
N/A | |
Enrolling by invitation |
NCT06029413 -
Myo vs. Myofascial Injection for Myofascial Trigger Points
|
N/A | |
Not yet recruiting |
NCT05637047 -
Pulsed Radiofrequency vs Dry Needling in Myofascial Pain
|
N/A | |
Completed |
NCT04057781 -
Pain and Neck Dysfunction Following Dry Needling With and Without Intramuscular Electrical Stimulus.
|
N/A | |
Recruiting |
NCT06036524 -
Multi-modal Imaging of Myofascial Pain
|
N/A | |
Completed |
NCT04897581 -
BBTI vs PSR in Musculoskeletal Orofacial Pain Adults
|
N/A | |
Completed |
NCT03398486 -
The Effectiveness of Kinesiotaping and Inactivation of Trigger Points in Chronic Myofascial Pain of TMD
|
N/A | |
Recruiting |
NCT05928884 -
Ultrasound Imaging for Myofascial Pain
|
||
Completed |
NCT04790071 -
Dry Needling Treatment in Hemiplegic Shoulder Pain
|
N/A | |
Completed |
NCT03704311 -
Evaluation of Mitochondrial Function in Myofascial Trigger Points Cohort Pilot Study Using High-resolution Respirometry
|
N/A | |
Completed |
NCT05365932 -
Evaluation of an Intra Auricular Device as a Treatment for Painful Temporo-Mandibular Disorders
|
N/A | |
Completed |
NCT04628286 -
Myofascial Induction Effects on Stabilometry Versus Sham Laser
|
N/A | |
Completed |
NCT04628299 -
Effects of the Myofascial Induction Technique Versus a Control Laser
|
N/A | |
Completed |
NCT04884152 -
Telerehabilitation in Individuals Temporomandibular Dysfunction With Bruxism
|
N/A | |
Completed |
NCT01850420 -
A Study of IMC-1 In Patients With Fibromyalgia
|
Phase 2 | |
Terminated |
NCT03028012 -
TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone
|
Phase 4 | |
Completed |
NCT04929171 -
Myofascial Pain and Central Sensitization
|
||
Completed |
NCT04040309 -
PRGF Effectiveness for Myofascial Pain Treatment in Masticatory Muscles
|
Phase 4 | |
Completed |
NCT03651141 -
The Effects of Soft Tissue Therapy and Exercise on Hamstring Tightness
|
N/A | |
Recruiting |
NCT03885791 -
Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain
|
N/A |