Myofascial Pain Clinical Trial
— MitoTriggerOfficial title:
Evaluation of Mitochondrial Function in Chronic Myofascial Trigger Points - A Prospective Cohort Pilot Study Using High-resolution Respirometry
Verified date | October 2018 |
Source | Medical University Innsbruck |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This pilot study established a minimally invasive biopsy technique to obtain high-quality MTrP tissue samples to evaluate mitochondrial function via high-resolution respirometry.
Status | Completed |
Enrollment | 20 |
Est. completion date | December 1, 2014 |
Est. primary completion date | February 1, 2014 |
Accepts healthy volunteers | No |
Gender | Male |
Age group | 18 Years to 45 Years |
Eligibility |
Inclusion Criteria: - Male patients aged 18-45 years - Clinical diagnosis of myofascial pain syndrome within the region of the shoulder-neck muscles or the lumbogluteal region and the presence of an MTrP, defined as a firm palpation of a hard, tender nodule resulting in a spontaneous pain complaint - with symptoms present for 1 to 12 months Exclusion Criteria: - Signs that the participant's prescriptive compliance was not expected (e.g., lack of cooperation) - Disorders of the respiratory tract - Neurological disorders, in particular neurodegenerative and neuromuscular diseases - Disorders of the cardiovascular system or the musculoskeletal system - Civil servants and military service personnel. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Medical University Innsbruck |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mitochondrial function in myofascial trigger points | Mitochondrial respiration was assessed from muscle biopsy samples obtained from trigger points of the musculus trapezius and the musculus gluteus medius | Baseline measurement | |
Secondary | Number of participants with biopsy-related impaired wound healing | Clinical wound assessment (number of patients with signs for local infection and inflammation) | Baseline and follow-up assessment (1 week after the baseline biopsy) |
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