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Myelomonocytic Leukemia clinical trials

View clinical trials related to Myelomonocytic Leukemia.

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NCT ID: NCT04775121 Completed - Clinical trials for Myelomonocytic Leukemia

Classical Monocyte Kinetics in Chronic Myelomonocytic Leukemia

MONOLIFE
Start date: May 13, 2019
Phase: N/A
Study type: Interventional

To measure the rate of bone marrow release and the lifespan of classical monocytes in the peripheral blood of patients with a chronic myelomonocytic leukemia

NCT ID: NCT01776723 Completed - Clinical trials for Myelomonocytic Leukemia

A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib

Start date: February 20, 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to find out if treating Chronic Myelomonocytic Leukemia (CMML) with a study drug [ruxolitinib] can improve outcomes of patients with CMML. The first step of the study is to learn the dose of ruxolitinib that is tolerable (bearable). It has already been studied in a number of patients with different bone marrow diseases and is approved for the treatment of a disease called Myelofibrosis; however, it is not approved for treatment of CMML. It is given orally (by mouth). Most people tolerate it well but the tolerability has not been determined in patients with CMML. We will be testing different doses to determine how much of the medication people can tolerate (bear) before they develop side effects.