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Lenalidomide, Dexamethasone and MEDI-551 in Untreated Multiple Myeloma

Myeloma Clinical Trial

Official title:
Pilot Study of Lenalidomide and Dexamethasone in Combination With MEDI-551 in Previously Untreated Multiple Myeloma.

Clinical Trial Summary

This research study is being done to see if combining the investigational chemotherapy drug, MEDI-551 with the known anti-myeloma drugs, Lenalidomide and Dexamethasone will reduce your myeloma cancer stem cells.

Clinical Trial Description

To explore the effect of Lenalidomide, dexamethasone and Medi-551 on multiple myeloma cancer stem cells (CSCs). Myeloma CSCs will be assessed by a clonogenic assay from the bone marrow and flow cytometry from peripheral blood. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01861340
Study type Interventional
Source Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Contact
Status Completed
Phase Early Phase 1
Start date May 2014
Completion date July 2016
View Details
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