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Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers — UK-Haplo  

Myelodysplastic Syndrome Clinical Trial

Official title:
A UK Multicentre Study of Haploidentical Stem Cell Transplantation in Patients With Haematological Malignancies

Clinical Trial Summary

This trial investigates stem cell transplants from partially mismatched donors in patients with blood and bone marrow cancers. The trial will test two kinds of transplants - a full intensity transplant using a high dose of radiotherapy and chemotherapy, and a reduced intensity transplant with lower doses of chemotherapy and radiotherapy. Patients will be entered for the treatment pathway that is most appropriate for their level of health and fitness

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Acquired Bone Marrow Failure Syndromes
  • Acute Lymphoblastic Leukaemia
  • Acute Myeloid Leukaemia
  • Bone Marrow Failure Disorders
  • Chronic Lymphocytic Leukaemia
  • Chronic Myeloid Leukaemia
  • Hematologic Neoplasms
  • Hodgkin's Lymphoma
  • Leukemia
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
  • Leukemia, Myeloid
  • Lymphoma
  • Myelodysplastic Syndrome
  • Myelodysplastic Syndromes
  • Neoplasms
  • Non-Hodgkin's Lymphoma
  • Other Haematological Malignancies; Unrelated HSCT Indicated
  • Pancytopenia
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Syndrome
Clinical Trial Details
NCT number NCT01597219
Study type Interventional
Source University College, London
Contact
Status Completed
Phase Phase 2
Start date March 2013
Completion date January 2024
View Details
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