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Human Placental-Derived Stem Cell Transplantation — HPDSC  

Myelodysplastic Syndrome Clinical Trial

Official title:
A Single-Arm Study to Assess the Safety of Transplantation With Human Placental-Derived Stem-Cells Combined With Unrelated and Related Cord Blood in Subjects With Certain Malignant Hematologic Diseases and Non-Malignant Disorders

Clinical Trial Summary

The purpose of this clinical trial is to investigate the safety of human placental-derived stem cells (HPDSC) given in conjunction with umbilical cord blood (UCB) stem cells in patients with various malignant or nonmalignant disorders who require a stem cell transplant. Patients will get either full dose (high-intensity) or lower dose (low intensity) chemo- and immunotherapy followed by a stem cell transplantation with UCB and HPDSC.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Acute Lymphocytic Leukemia
  • Acute Myelogenous Leukemia
  • Adrenoleukodystrophy
  • Amegakaryocytic Thrombocytopenia
  • Anemia
  • Anemia, Aplastic
  • Anemia, Diamond-Blackfan
  • Batten Disease
  • Diamond-Blackfan Anemia
  • Fucosidosis
  • Gaucher Disease
  • Gaucher's Disease
  • Krabbe's Disease
  • Leukemia
  • Leukemia, Myeloid
  • Leukemia, Myeloid, Acute
  • Leukodystrophy, Globoid Cell
  • Leukodystrophy, Metachromatic
  • Metachromatic Leukodystrophy
  • Mucopolysaccharidoses
  • Mucopolysaccharidosis I
  • Mucopolysaccharidosis VI
  • Myelodysplastic Syndrome
  • Myelodysplastic Syndromes
  • Neuronal Ceroid-Lipofuscinoses
  • Niemann-Pick Disease
  • Niemann-Pick Disease, Type C
  • Niemann-Pick Diseases
  • Pick Disease of the Brain
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Severe Aplastic Anemia
  • Thrombocytopenia
  • Wolman Disease
Clinical Trial Details
NCT number NCT01586455
Study type Interventional
Source New York Medical College
Contact
Status Completed
Phase Phase 1
Start date April 2013
Completion date September 2022
View Details
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