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Efficacy of Apraclonidine Eye Drops in the Treatment of Ptosis Secondary to Myasthenia Gravis

Myasthenia Gravis Clinical Trial

Official title:
Efficacy of Apraclonidine Eye Drops in the Treatment of Ptosis Secondary to Myasthenia Gravis

Clinical Trial Summary

This study is aimed at assessing the efficacy of Apraclonidine eye drops in the treatment of ptosis secondary to myasthenia gravis.

Clinical Trial Description

The rationale behind using Apraclonidine is that it acts on Muller's muscle which is a sympathetic-innervated muscle. As such, this muscle is expected to be spared from the effects of the autoantibodies that attack the postsynaptic portion of the neuromuscular junction in myasthenia gravis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05045248
Study type Interventional
Source American University of Beirut Medical Center
Contact
Status Completed
Phase Phase 2
Start date June 1, 2020
Completion date April 15, 2021
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