Clinical Trials Logo

Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT02362685
Other study ID # RANNOU
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date September 2008
Est. completion date December 2027

Study information

Verified date January 2020
Source University Hospital, Brest
Contact Fabrice Rannou, MD, PhD
Phone 33(0)298347366
Email fabrice.rannou@chu-brest.fr
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Exertional symptoms are the hallmarks of metabolic myopathies, supporting the concept of using functional tests when this diagnosis is suspected. Exercise increases the concentration of muscle metabolites in the venous blood supply (e.g. lactate, pyruvate, and ammonia) especially during recovery. The purpose of this study is to compare the results of exercise testing with to the data from muscle biopsy or genetic analysis.


Recruitment information / eligibility

Status Recruiting
Enrollment 1000
Est. completion date December 2027
Est. primary completion date December 2027
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 5 Years and older
Eligibility Inclusion Criteria:

- Referred to the Physiology Department of Brest Hospital for a metabolic exercise test

- Ability to provide informed consent

Exclusion Criteria:

- Contraindication(s) to perform cardiopulmonary exercise testing (ATS/ACCP statement on cardiopulmonary exercise testing, Am J respi Care Med 167: 211-77, 2003)

- Pregnancy or unknown pregnancy status.

Study Design


Intervention

Device:
functional test
subjects perform a metabolic exercise testing
Genetic:
matching genotype with phenotype


Locations

Country Name City State
France Centre Hospitalier Régional Universitaire Brest

Sponsors (1)

Lead Sponsor Collaborator
University Hospital, Brest

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary Whole-body dynamic exercise The relation between Cardiopulmonary exercise test variables and the results of muscle biopsy or genetic analysis will be evaluated. Participants will be followed for an expected average of 1 year to determine whether a muscle biopsy is performed
Primary Grip-test The relation between Grip-test variables and the results of muscle biopsy or genetic analysis will be evaluated. Participants will be followed for an expected average of 1 year to determine whether a muscle biopsy is performed
Primary Blood tests The results of blood analysis from samples performed before, during, and after exercise will be compared to the results of muscle biopsy or genetic analysis. Participants will be followed for an expected average of 1 year to determine whether a muscle biopsy is performed
See also
  Status Clinical Trial Phase
Recruiting NCT05033613 - Home Blood Pressure Monitoring Before and After COVID-19 Vaccination in Patients at High Risk of Cardiovascular Disease
Recruiting NCT03849534 - Treatment of Temporomandibular Disorders in Children and Adolsecents N/A
Completed NCT04897581 - BBTI vs PSR in Musculoskeletal Orofacial Pain Adults N/A
Completed NCT00957996 - Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza Phase 3
Completed NCT04581395 - The Effect of Pretreatment With Roc on Succinylcholine Myalgias Phase 3
Completed NCT01026311 - Coenzyme Q10 in Older Athletes Treated With Statin Medications Phase 4
Completed NCT01506583 - Clinical Evaluation of QFlu Combo Test
Completed NCT04797936 - BNO 1030 Extract (Imupret) in the Treatment of Mild Forms of COVID-19 Phase 4
Terminated NCT02685202 - Temporomandibular Disorder (TMD) Pain in Response to Jaw Advancement in People With TMD and Obstructive Sleep Apnea N/A
Completed NCT01279590 - Study of the Safety and Tolerability Associated With PPD10558 Versus Atorvastatin in Patients Previously Intolerant to Statins Due to Statin-associated Myalgia (SAM) Phase 2
Recruiting NCT04806191 - Simple and Evidence-based Examination and Treatment of Shoulder Pain in General Practice N/A
Enrolling by invitation NCT06405646 - Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
Not yet recruiting NCT01097798 - To Evaluate the Efficacy and Safety Aliviador Compared to Gelol in Patients With Contusions, Sprains, Trauma and Muscle Injury. Phase 3
Not yet recruiting NCT05961501 - The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin Phase 2/Phase 3
Completed NCT05448209 - The Effect of Walking Exercise Based on TOUS on Peripheral Neuropathy and Arthralgia-Myalgia in Women With Breast Cancer N/A
Not yet recruiting NCT03566394 - Prophylactic Gabapentin for Taxane-Induced Arthralgia and Myalgia Syndrome in Breast Cancer Patients Undergoing Adjuvant Chemotherapy Phase 2/Phase 3
Not yet recruiting NCT04426123 - Masseter Myofascial Pain Relief Following an Intra-muscular Injection With Botulinum Toxin Type A. Phase 2
Completed NCT04737278 - Safety and Efficacy of Cunermuspir on Energy, Strength, and Fatigue in Patients With Nerve or Muscle Pain Phase 1/Phase 2
Recruiting NCT06125002 - Diosmin for Treatment of Delayed-onset Muscle Soreness (DOMS) Phase 1
Completed NCT03371888 - The Platelet-Rich Plasma in the Therapy of Temporomandibular Disorders Phase 2/Phase 3