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Biological and Functional Markers for Precision Astronautical Biomedicine — MARS-PRE  

Muscular Atrophy Clinical Trial

Official title:
MARS-PRE: MARcatori Biologici e Funzionali Per la Biomedicina aStronautica di PREcisione

Clinical Trial Summary

In the current study the investigators will study early biomarkers of human degradation. In 10-day horizontal bed rest the investigators will enroll 10 healthy male subjects (18-30years, BMI 20-28kg/m2). Pre-, mid- and post-bed rest the investigators will perform various measurements, some of them will be invasive (blood samples and muscle biopsies), which will be carefully taken by the medical staff. The subjects will be placed in hospital rooms and have 24-hour medical supervision, adequate hygiene, nutrition, passive exercise, entertainment and visits.

Clinical Trial Description

Ten young male participants will undergo 10 days of horizontal bed rest. Before, during and after the investigators will monitor many biomechanical, metabolic, cardiovascular, biochemical responses.

During the bed rest period there will be no interventions. subjects will be allowed to rotate freely, with no vertical stimulus of any-kind. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04081467
Study type Interventional
Source Science and Research Centre Koper
Contact
Status Completed
Phase N/A
Start date August 28, 2019
Completion date October 16, 2019
View Details
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