BFRT for Severe Lower Extremity Muscle Atrophy — BFRT  

Muscle Weakness Clinical Trial

Official title: Blood Flow Restriction Training for Severe Lower Extremity Muscle Atrophy

Status Completed

Clinical Trial Summary

Muscle weakness or atrophy is a common condition following acute and chronic musculoskeletal injuries. Strength training is an imperative component in clinical rehabilitation of musculoskeletal injuries. Heavy exercise loads (approximately 70% of one repetition maximum) is necessary to elicit muscle hypertrophy and strength gains. However, patients with severe muscle atrophy are frequently unable to tolerate these loads due to pain. Blood flow resistance training with low resistance loads may be used to safely develop muscle strength.

Clinical Trial Description

Blood flow restriction training (BFRT) is a safe type of low intensity resistance exercise that has demonstrated enhanced muscle growth, muscle strength, oxygen delivery and utilization (VO2Max). With BFRT, lighter loads can be used to build muscle while sparing the joints from heavy loading and without overly fatiguing the central nervous system. The objectives of BFRT are 1) to increase the effectiveness of physical therapy, 2) safely increase muscle mass, reduce arterial stiffness, increase bone density, increase Vo2Max, improve carotid arterial compliance and enhance response of the autonomic nervous system, 3) improve muscle endurance in 1/3 the time, improve strength and hypertrophy after surgery, improve muscle recruitment and increase anabolic growth signaling. ;

Related Conditions & MeSH terms

• Atrophy
• Muscle Weakness
• Muscular Atrophy
• Severe Muscle Atrophy

• NCT number: NCT04357184
• Study type: Interventional
• Source: Cincinnati Sportsmedicine Research and Education Foundation
• Status: Completed
• Phase: N/A
• Start date: April 14, 2020
• Completion date: February 15, 2022