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Influence of Non-steroidal Anti-inflammatory Drugs (NSAID) on Muscle Regeneration

Muscle Damage Clinical Trial

Official title:
The Influence of Blocking Inflammatory Activity in Vivo on Skeletal Muscle Regeneration in Humans

Clinical Trial Summary

The purpose of this study is to determine the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on muscle regeneration.

The investigators' hypothesis is that ingestion of NSAID will delay or impair muscle regeneration.

Clinical Trial Description

The model employed to induce muscle damage is electrical stimulation. Muscle biopsies will be examined to follow the response of satellite cells and muscle regeneration. Study participants will be randomly assigned to a placebo or NSAID group in a double-blinded manner. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00832663
Study type Interventional
Source Bispebjerg Hospital
Contact
Status Completed
Phase N/A
Start date April 2009
Completion date December 2009
View Details
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