Muscle Cramp Clinical Trial
Official title:
The RELAX Trial: Nonpharmaceutical Intervention for Nocturnal Muscle Cramps
The purpose of the study is to learn about reducing the symptoms and severity of nighttime lower body muscle cramps in patients with and without cirrhosis. Eligible participants will have an initial 7-day practice phase, followed by 28 days of one of two behavioral interventions.
The interventions in this trial can be done at home. Openly discussing the intervention groups with all participants prior to randomization thus poses a high risk of tainting the study because subjects in the one group may start doing the other groups exercises after having heard about it during the consent process as a way to potentially reduce the symptoms and severity of painful muscle cramps. Therefore, this study will conceal information regarding the nature of the interventions. Only participants randomized to the true intervention group will be told during the study period what the behavioral intervention is. Additionally, the title of this trial upon registration is listed slightly differently than it is listed with the Institutional Review Board (IRB), to provide scientific integrity with the masking requirements. When the trial is completed, the title will be amended to match the IRB approved title. At the conclusion of the study, at the time of the final follow-up assessments, all participants will be debriefed on the use of the concealment of the study object in this study. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04998305 -
TJ-68 Clinical Trial in Patients With Amyotrophic Lateral Sclerosis (ALS) and Muscle Cramps
|
Phase 1/Phase 2 | |
Completed |
NCT03176966 -
Ropinirole for the Treatment of Muscle Cramps in Patients With Cirrhosis
|
Phase 4 | |
Completed |
NCT04575090 -
7 Tesla MRI Study in Patients With Statin Related Muscle Complaints
|
N/A | |
Completed |
NCT01271660 -
A Study Evaluating the Efficacy and Safety of Pregabalin Against Frequent Muscle Cramp in Patients With Liver Cirrhosis
|
Phase 3 | |
Terminated |
NCT00516516 -
Oral Carnitine for Cramps in Pregnancy
|
N/A | |
Completed |
NCT04650295 -
Non-Pharmaceutical Intervention for Cirrhotic Cramps Reduction: The NICCles Trial
|
N/A | |
Recruiting |
NCT03660969 -
Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease
|
||
Not yet recruiting |
NCT04694417 -
Prevention of Leg Cramps Using Compression Stockings or Magnesium Supplements in the Age Group of 50 to 84
|
N/A | |
Completed |
NCT03802565 -
Tolperisone in Acute Muscle Spasm of the Back
|
Phase 2 | |
Completed |
NCT04901832 -
Intradialytic Stretching Exercises on Prevention and Reduction of Leg Muscle Cramps
|
N/A | |
Terminated |
NCT04507373 -
7T Magnetic Resonance Spectroscopy and Skeletal Muscle Biopsy Findings in Statin Associated Adverse Muscle Events
|
Phase 4 | |
Completed |
NCT00963638 -
Beneficial Effects of Magnesium Supplementation On Idiopathic Muscle Cramps
|
N/A | |
Completed |
NCT05724485 -
Effect of Branched-chain Amino Acids (BCAA) to Muscle Cramps in Patients With Cirrhosis
|
Phase 4 |