Multiple Trauma Clinical Trial
Official title:
Central Venous-arterial Carbon Dioxide Pressure Difference in Correlation to Dynamic Changes of Serum Lactate as an Indicator of Tissue Perfusion in Polytruama Patients
Early intervention and resuscitation based upon a lot of clinical, laboratory findings make a big difference regarding outcome in poly trauma patients, the study uses the dynamic lactate change and the difference between arterial and venous CO2, oxygen tension or content as indicators for tissue perfusion.
Status | Recruiting |
Enrollment | 40 |
Est. completion date | January 2018 |
Est. primary completion date | September 2017 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 40 Years |
Eligibility |
Inclusion Criteria: - multiple trauma patients Adult patients Exclusion Criteria: - cardiac renal chronic chest disease diabetic more than 3 years |
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Country | Name | City | State |
---|---|---|---|
Egypt | Emad Zarief Kamel Said | Assiut |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | the difference between partial pressure of oxygen in arterial and venous blood | 6 hours | No | |
Primary | the difference between partial pressure of carbon dioxide in arterial and venous blood | 6 hours | No | |
Primary | serum level of lactate and its changes | as an index for tissue oxygenation | 6 hours | No |
Secondary | Kidney function | serum creatinine in mg/ dl and urine output/ hour | 72 hours | No |
Secondary | hemodynamic stability including pulse rate and mean arterial blood pressure | 72 hours | No | |
Secondary | duration of stay in the critical care unit | 72 hours | No |
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