Clinical Trials Logo
  1. Home
  2. Multiple Trauma
  3. NCT02030327
  4. Details
NCT02030327 Clinical Trial

Proteomics in Multiple Trauma to Identify Organ Failure

Multiple Trauma Clinical Trial

Official title:
Analysis of Predictive Parameters by Proteomics for Early Diagnosis of Organ Dysfunction in Multiple Trauma Patients - A Pilot Study

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT02030327
Other study ID # 12-236
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date January 2014
Est. completion date December 2022

Study information
Verified date May 2022
Source Universitätsklinikum Köln
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To analyse differences in protein expression in multiple trauma patients for identification of potential biomarkers to predict organ dysfunction.

Description:

The aim of the present study in humans is to analyse differences in protein expression after multiple trauma in patients for identification of potential biomarkers to predict organ dysfunction.

Recruitment information / eligibility
Status Recruiting
Enrollment 85
Est. completion date December 2022
Est. primary completion date December 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - older than 18 years - multiple trauma patients - ISS >16 Exclusion Criteria: - children - ISS <16

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Germany University Hospital of Cologne Cologne NRW

Sponsors (1)
Lead Sponsor Collaborator
Universitätsklinikum Köln

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of patients with disease or death vs. healthy Starting at day O, then every 24 hours until day 20 Day 0 until day 20
See also
  Status Clinical Trial Phase
Recruiting NCT02682550 - Danger Response in Polytrauma Patients N/A
Completed NCT03634215 - Estimation of Coagulation Factor XIII Activity Based on the Initial Plasma Fibrinogen Level in Trauma
Completed NCT00872690 - Factors Affecting Return to Work Among OEF/OIF Veterans With Polytrauma N/A
Completed NCT01669577 - Independent Predictors of Mortality in Polytrauma Patients Phase 3
Recruiting NCT04588311 - ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients Phase 3
Terminated NCT00613392 - Antioxidant Supplementation in Trauma Patients Phase 3
Completed NCT02917694 - A Feasibility Study to Assess Pre Admission Status and Six Month Outcomes After Major Trauma
Recruiting NCT05386199 - The Role of Serotonin in Intensive Care Patients
Recruiting NCT02727946 - Tissue Perfusion Indices as Predictor of Outcome in Poly Trauma Patients N/A
Completed NCT03480555 - Replacing Protein Via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients N/A
Recruiting NCT03368092 - Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma Phase 3
Recruiting NCT01240291 - The Clinical Role of Intravenous Glutamine in Trauma Patients Receiving Enteral Nutrition Phase 3
Not yet recruiting NCT01074112 - Keller Prehospital Ultrasound Study N/A
Completed NCT00163826 - Spinal Clearance Study: Expediting the Spinal Clearance Process in the Major Trauma Patient Phase 4
Completed NCT05630222 - Evaluation of Effect of Intravenous Morphine vs Intravenous Ibuprofen and Acetaminophen vs Intravenous Ibuprofen Phase 3
Terminated NCT03489577 - The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients
Terminated NCT01477697 - Effects of Omega-3 Fatty Acid Supplementation on Inflammatory Response in Multisystem Trauma Patients Phase 1/Phase 2
Completed NCT01373996 - Clinical Investigation of Wireless Transmission of Invasive Blood Pressure Signal N/A
Completed NCT03154424 - Dynamic External Fixation in Treatment Distal Radius Fractures - Elderly Patients N/A
Recruiting NCT00459160 - A Comparison of Two Target Mean Arterial Pressures in the Resuscitation of Hypotensive Trauma Patients N/A