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A Study of End of Dose Phenomena in Subcutaneous Natalizumab Treated Multiple Sclerosis (MS) Participants — SATURATE-MS  

Multiple Sclerosis Clinical Trial

Official title:
End of Dose Phenomena in Subcutaneous Natalizumab Treated MS Patients

Clinical Trial Summary

The primary objective of this study is to better understand the pathophysiological background of end-of-dose symptoms (EOD) and thereby determine the percentage of participants who develop EOD under natalizumab (NTZ) as an example of interval therapy in MS and to detect specific changes through multimodal analyses, including radiological, blood and digital health measurements, that may be used as potential biomarkers in the future to map EOD.

Clinical Trial Description

Participants will additionally be offered to record daily activity and sleep patterns as well as heart rate for the duration of the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05701423
Study type Observational
Source Biogen
Contact
Status Active, not recruiting
Phase
Start date February 8, 2023
Completion date July 31, 2024
View Details
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