Vancomycin Study in Multiple Sclerosis (MS)

Status Recruiting

Clinical Trial Summary

The overall goal of this study is to elucidate a mechanism by which vancomycin modulates the gut-brain axis in multiple sclerosis (MS). The gut microbiome plays an important role in autoimmunity, including MS. However, the identity of gut microbes modulating neuroinflammation in MS and their mechanisms of action remain obscure. Hence, here the research team proposes to investigate the effects of vancomycin on the gut microbiota composition, peripheral immune function, and brain MRI lesions in MS patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05539729
Study type	Interventional
Source	Icahn School of Medicine at Mount Sinai
Contact	Susan E Filomena, BA
Phone	212-2413841
Email	susan.filomena@mssm.edu
Status	Recruiting
Phase	Phase 1
Start date	February 8, 2023
Completion date	December 2027

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