Multiple Sclerosis Clinical Trial
Official title:
Effects of Dual-Task Training on Balance, Gait, Dual-Task Performance, Cognitive Function, Fatigue in People With Multiple Sclerosis
The purpose of this study is to investigate the effects of dual task training on balance, gait, dual-task performance, cognitive function, fatigue and functional mobility in people with Multiple Sclerosis(MS).
Status | Recruiting |
Enrollment | 26 |
Est. completion date | August 15, 2023 |
Est. primary completion date | April 1, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Having a definitive diagnosis of MS according to the revised McDonald criteria - Having Expanded Disability Status Scale score between 0-5.5 - No relapse in the last 30 days - Having a Mini Mental Test score of 24 and above - Being fluent in Turkish language - No condition that prevents exercising Exclusion Criteria: - Being pregnant - Presence of a neuro-musculoskeletal disease other than Multiple Sclerosis - Having received physiotherapy for balance and gait disorders in the last 3 months |
Country | Name | City | State |
---|---|---|---|
Turkey | Ege University Faculty of Health Sciences | Izmir | Karsiyaka |
Lead Sponsor | Collaborator |
---|---|
Ege University |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Berg Balance Scale(BBS) | BBS, evaluates daily activities including static sitting and standing balance, as well as transfers, turning, and picking up objects from the ground, in 14 items.Scoring is given as 0-4. It scores from 4 (normal performance) to 0 (not able to do the movement) according to the person's ability to do what is asked of them safely and independently. The total score is 56 points. 0-20 indicates high risk, 21-40 indicates medium risk, and 41-64 indicates low risk. | eight weeks | |
Primary | Timed Up And Go Test (TUG) | It is a frequently used test that evaluates functional mobility and dynamic balance. At the beginning of the test, individuals sit in a chair. A distance of 3 m is set in front of the patient. With the start command, the patient gets up from his seat and walks 3 m, turns around and walks back and sits. With the start command, the time until the moment of sitting on the chair is recorded in seconds.Shorter duration indicates better functional mobility. | eight weeks | |
Primary | Tetrax((Sunlight Medical Ltd, Israel),Computerized Static Posturography Device | Tetrax (Sunlight Medical Ltd, Israel) computerized posturography device consists of a platform system where data is collected, a computer and software system where data is processed and integrated. Participants will stand on the platform system in 8 different condition. Tetrax will be used to measure static balance and fall risk. | eight weeks | |
Secondary | MS Walking Scale-12(MSWS-12) | MSWS-12 is a 12-item scale evaluating the effect of MS on person's walking ability. MSWS-12 is scored between 12-54. Higher scores indicate more negatively affected walking ability. | eight weeks | |
Secondary | Fatigue Severity Index(FSI) | The scale consists of 9 questions and each question is graded over 7 points.FSI is scored between 0-63. Higher scores indicate more fatigue. | eight weeks | |
Secondary | Brief International Cognitive Assesment for MS(BICAMS) | BICAMS includes Symbol Digit Modalities Test (SDMT), California Verbal Learning Test II (CVLT-II) and Brief Visuospatial Memory Test-Revised (BVMT-R). The total score is determined by summing the scores of the 3 tests. Battery will be used to evaluate cognitive function. Higher scores indicate better cognitive function. | eight weeks | |
Secondary | 10 Meter Walking Test(10MWT) | This test calculates the unassisted walking speed of individuals at a distance of 10 meters. In this test, the person will be asked to walk at their normal pace in a pre-measured 10 meter area. | eight weeks | |
Secondary | Dual-Task Performance | Dual-Task performance will be measured with TUG-cognitive and 10MWT-motor. In TUG-cognitive,patient will be counting down by three from a number between 100 and 200 while performing Timed-Up and Go test. In 10MWT-motor,patient will be carrying a tray with 3 water filled 200 ml plastic glasses while walking a 10 m distance.Time will be measured. Longer time to complete task indicates lower dual-task performance. | eight weeks | |
Secondary | Dual-Task Questionnaire(DTQ) | The Dual Task Questionnaire assesses the frequency of difficulties experienced by individuals with neurological injury or disease during activities of daily living that involve dual tasks. DTQ is scored between 0-40. Higher scores indicate more frequent dual-task difficulties. | eight weeks |
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