Multiple Sclerosis Clinical Trial
— EPSMSOfficial title:
Exploratory Study of Entire-body PET Scans for Multiple Sclerosis
To evaluate whether an entire-body positron emission tomography (PET) scanner can be exploited to improve evaluation, monitoring and measurement of both peripheral and central demyelination in multiple sclerosis (MS) patients.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | October 30, 2024 |
Est. primary completion date | April 30, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 25 Years to 55 Years |
Eligibility | Inclusion Criteria: - Multiple sclerosis (MS) patients diagnosed by a credentialed neurologist experienced with care of multiple sclerosis patients. - Normal healthy subjects. - Willing and able to lie motionless on the PET-CT scanner bed for at least 10 minutes and up to 20 minutes for the duration of the PET-CT medical imaging scan. Exclusion Criteria: - Any additional complicating medical illness other than MS including any other neuropsychiatric illness unrelated to MS diagnosed prior to the onset of initial symptoms of MS. - Pregnancy or breast feeding. - Diabetes or other metabolic-endocrine disorders. - Any known concomitant acute infection. - History of metastatic or locally invasive cancer. - Recent surgery, chemotherapy or radiation therapy. |
Country | Name | City | State |
---|---|---|---|
United States | Brain Health Alliance | Ladera Ranch | California |
Lead Sponsor | Collaborator |
---|---|
Brain Health Alliance |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Entire-body PET imaging of demyelination of peripheral and central nervous system | Exploratory analysis of relative regional increases and/or decreases of Amyvid activity | During 1 day single PET-CT scan | |
Primary | Psychometric questionnaire for monitoring psychological health | Assessments of participants | Up to 90 days |
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