Multiple Sclerosis Clinical Trial
Official title:
Sexual Dysfunction in Patients With Relapsing Remitting Multiple Sclerosis and Associated Comorbidities
This work aims to:
1. Investigate and correlate Sexual Dysfunction in relapsing-remitting Multiple Sclerosis
patients with specific focus on
1. Specific neurologic deficit.
2. Depressive symptoms.
3. Comorbid factors.
4. Fatigue symptoms.
2. To investigate the impact of Sexual dysfunction on Sexual Quality of Life (SQoL).
3. To search for possible gender difference.
The present study is a cross sectional study on 120 MS adolescent patients meeting the
McDonald's criteria; 60 male cases and 60 female cases recruited from Mansoura University
Hospitals, Egypt.
All patients were subjected to the following:
1. Clinical Evaluation:
1. Thorough neurological examination.
2. Cognitive functions by Minimental State Examination (MMSE).
e. Expanded Disability Severity Scale (EDSS).
2. Neurophysiological Evaluation:
a. Visual Evoked Potential (VEP).
3. Imaging Evaluation:
a. Conventional MRI.
4. Cerebrospinal Fluid (CSF):
5. Sexual dysfunction measure: through the international index of erectile function (IIEF),
female sexual function questionnaire (SFQ) and the sexual Quality of life male and
female version (SQoL) (American Psychiatric Association, 1994).
6. Depressive symptoms assessment through The BDI (The Beck Depression Inventory) which is
the most common instrument measuring the severity of depression.
7. Fatigue symptoms were evaluated through fatigue subscale of Multiple Sclerosis Quality
of Life-54(MSQOL-54).
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