The Effect of Cognitive Group Exercise Combined With Physical Exercise in MS

Multiple Sclerosis Clinical Trial

Official title:

The Effect of Cognitive Group Exercise Combined With Physical Exercise in Multiple Sclerosis Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04075968
• Other study ID #: IstanbulPMRTRH
• Status: Completed
• Start date: December 1, 2018
• Est. completion date: December 1, 2019

Study information

• Verified date: February 2021
• Source: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this study is to investigate the effect of cognitive rehabilitation in group with physical exercise in patients with Multiple Sclerosis. We assume that cognitive therapy is an effective treatment for multiple sclerosis.

Description:

The aim of this study is to investigate the effect of cognitive rehabilitation in group with physical exercise in patients with Multiple Sclerosis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: December 1, 2019
• Est. primary completion date: November 15, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 65 Years

Eligibility

Inclusion Criteria:

• Patients with an Mini Mental State Test score less than 24
• Patients with an Extended Disability Status Scale score less than 4
• Patients trained for at least 5 years
• Patients who have not received steroid therapy in the last 1 month

Exclusion Criteria:

• Patients who have not passed at least 3 months from the last Multiple Sclerosis attack
• Patients with hearing and vision problems that may interfere with communication
• The patients who Have other neurological and psychiatric disorder that will cause cognitive impairment
• Patients receiving medical treatment for spasticity, tremor, bladder disorder and fatigue

Related Conditions & MeSH terms

• Multiple Sclerosis
• Sclerosis

Intervention

Other:
• Cognitive exercise
Cognitive exercise will be applied
• Home exercise
Home exercise will be applied

Locations

Country	Name	City	State
Turkey	Health Sciences University Istanbul Physical Therapy and Rehabilitation Training and Research Hospital	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Neuro-psychometric Test (NPT)	It is a test that evaluates memory, working memory, planning, organization, attendance span.Evaluation is made according to the number of items filled. The higher number items filled indicates the better status	1 hour
Primary	Berg Balance Scale	It is a scale which consists of 14 items. Each item is scored on a five-point scale (0-4).The maximum score for this assessment is 56 and the minimum score for this assessment is 0. Scores below 45 indicate balance impairment. The higher point indicates the better status	15 minutes
Primary	Mini Mental State Test (MMST)	It is a test that evaluates different subset of cognitive status including attention, memory, language, orientation, visuospatial proficiency. It is scored on a scale of 0-30 with scores. Scores above 25 are interpreted as normal cognitive status.	10-15 minutes
Secondary	Modified Ashworth Scale (MAS)	The MAS is a 6-point rating scale which assesses muscle tone by manually manipulating the joint through its available range of motion and clinically recording the resistance to passive movements. The lower point indicates the better status	3 minutes