Multiple Sclerosis Clinical Trial
Official title:
The Effects of Extremity and "Core" Muscles Strength on Walking and Sit-to-Stand Performance in Patients With Multiple Sclerosis
Muscle weakness, which is one of the most common symptoms in patients with MS, limits the
activities of daily life activities of patients by causing balance and gait disturbance.
Lower extremity muscle strengths of MS patients are reported to be weaker than healthy
individuals. Broekmans et al. showed that the weakness of the knee flexor and extensor
muscles in patients with MS caused a decrease in walking distance and they are important
determinants of walking capacity.
The effects of the endurance and strength of core muscles, as well as the extremity muscles,
are important on physical performance. The weakness of the extremities and core muscles in MS
patients also affects the sit-to-stand performance negatively as well as a decrease in
walking speed and capacity.
In this study, it was aimed to investigate the effects of extremity and core muscle strength
on walking and sitting-up performance of MS patients.
Patients with MS between 0-5,5 score according to the Extended Disability Status Scale (EDSS)
and healthy individuals of similar age and sex to patients will be included in the study. The
strength of the extremity and core muscles, walking capacity, and sit-to-stand performance
will be evaluated once.
Investigators will use descriptive statistics and t-tests to compare variables between
groups. Investigators will examine the correlations between variables using Pearson bivariate
correlations. The significance level is set at p<0,05
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