Multiple Sclerosis Clinical Trial
Official title:
Real-Life Outcomes of Multiple Sclerosis Treatment With Rebif on Employment Status, Quality of Life and Cognition: a Pilot Study
The purpose of this study is to determine whether Rebif has an impact on employment status, quality of life and cognition.
With this study the investigator plans to evaluate the impact of Rebif on the Real-Life
Outcomes (RLO) of Multiple Sclerosis (MS) patients followed at the Clinic within the last
two years, and with a follow-up of up to 18 years.
The investigator will evaluate the employment outcomes with a questionnaire designed to
document eventual changes in the employment status and other variables in the work
conditions of the study participants.
Furthermore, to evaluate the quality of life (QoL),eligible patients will be asked to
complete the Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument, contains 52 items
distributed into 12 scales, and two single items. This MS-specific QoL assessment tool uses
the Short Form Health Survey (SF-36) as its generic core measure and includes 18 additional
items under the following categories: health distress, sexual function, satisfaction with
sexual function (one item), overall quality of life, cognitive function, energy, pain, and
social function.
A sub-group of patients will be selected to come to the clinic to undergo the cognitive
portion of the study, using the well-known and validated battery of tests named Minimal
Assessment of Cognitive Function in MS (MACFIMS battery).
Socio-demographic data on education level, marital and family life will also be collected.
All questionnaires (including the MSQoL-54) will be available by means of an online survey.
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