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Resistance Training and Amino Pyridine in Multiple Sclerosis — RETRAP  

Multiple Sclerosis Clinical Trial

Official title:
RETRAP - A Double Blind, Randomized, Placebo Controlled Study of the Effect of the Combination of Resistance Training and Prolonged Release Fampridine in Patients With Multiple Sclerosis

Clinical Trial Summary

Prolonged-release fampridine (SR-fampridine) can improving walking capacity in approximately 40% of MS patients suffering from this by overcoming partly or total conduction block due to demyelination.

Resistance training has been shown to provide the same kind of benefits for patients by targeting the muscular component of the motor unit. Thus by combining the two it is likely to see an synergistic effect.

This trial is designed as a double blind, randomized placebo controlled trial with subsequent cross-over.

Participants in the two arms will go through the same progressive training program targets at the lower limbs. For 24 weeks one group receives SR-fampridine and the other receives placebo. in the the end there is another four weeks of training after cross-over has been performed.

Clinical Trial Description

See above ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02143167
Study type Interventional
Source University of Southern Denmark
Contact
Status Completed
Phase Phase 4
Start date May 2014
Completion date January 2015
View Details
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