Improving Gait in Multiple Sclerosis (MS) - Strength Training or Treadmill Walking?

Multiple Sclerosis Clinical Trial

Official title:

Strength Training or Treadmill Walking? A Randomized Control Study on the Effect on Gait in Multiple Sclerosis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01074827
• Other study ID #: 09/225
• Status: Completed
• Phase: N/A
• First received: February 23, 2010
• Last updated: July 6, 2015
• Start date: March 2010
• Est. completion date: April 2011

Study information

• Verified date: July 2015
• Source: St. Olavs Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway: Norwegian Social Science Data Services
• Study type: Interventional

Clinical Trial Summary

The objective of this study is to evaluate the effect of strength training for the lower extremities and treadmill training on walking ability in persons with Multiple Sclerosis. The study is a randomized control trial with two groups and the intervention is 8 weeks of intensive strength training or treadmill walking. Primary outcome measure is walking ability, secondary outcome measures are balance, work economy and strength.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 28
• Est. completion date: April 2011
• Est. primary completion date: April 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Diagnosed with Multiple Sclerosis,classified as relapsing remitting,or primary/secondary progressive

• Expanded Disability Status Scale (EDSS)score of = 6

• Reduced walking ability (subjectively experienced)

Exclusion Criteria:

• persons with a level of ataxia, clinically assessed, that would affect their ability to perform the training.

• spasticity requiring stretching og treatment with baclofen.

• Other, not MS-related, conditions affecting walking ability.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Multiple Sclerosis
• Sclerosis

Intervention

Other:
• Strength training and treadmill training
Eight weeks of intensive strength training or treadmill training

Locations

Country	Name	City	State
Norway	St. Olavs Hospital	Trondheim

Sponsors (3)

Lead Sponsor	Collaborator
St. Olavs Hospital	Helse Midt-Norge, Norwegian University of Science and Technology

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Braendvik SM, Koret T, Helbostad JL, Lorås H, Bråthen G, Hovdal HO, Aamot IL. Treadmill Training or Progressive Strength Training to Improve Walking in People with Multiple Sclerosis? A Randomized Parallel Group Trial. Physiother Res Int. 2015 Jun 25. doi — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Walking ability		8 weeks	No
Secondary	Strength		8 weeks	No
Secondary	Work economy O2		8 weeks	No
Secondary	Balance		8 weeks	No