Exercise Effects in Multiple Sclerosis

Status Recruiting

Clinical Trial Summary

A growing body of work suggests that regular exercise can support symptom management and improve physical function for people living with multiple sclerosis (MS). Although exercise is known to be beneficial for managing many symptoms related to MS, its effects on the central nervous system, and whether these effects change with different types of exercise, are not well understood. Here, the investigators have designed a clinical trial that compares the effects of distinct exercise protocols on aspects of physical function, physical fitness, and central nervous system function. This research will be the first to compare the effects of different types of exercise on central nervous system changes in people with MS.

Clinical Trial Description

A total of 69 participants with multiple sclerosis (MS) and moderate motor disability in the province of Saskatchewan, Canada will be randomly assigned to receive one of three distinct exercise programs. All exercise programs will be delivered three times per week in 60-minute group sessions over the course of 12 weeks under the supervision of Clinical Exercise Physiologists. Exercise programming will include activities focused on mobility, fitness, and flexibility. Assessments of physical function, physical fitness, and central nervous system function will be conducted immediately before, after, and six weeks following completion of the exercise programs. ;

Study Design

Related Conditions & MeSH terms

Multiple Sclerosis
Multiple Sclerosis, Chronic Progressive
Multiple Sclerosis, Primary Progressive
Multiple Sclerosis, Relapsing-Remitting
Multiple Sclerosis, Secondary Progressive
Sclerosis

Clinical Trial Details

NCT number	NCT05496881
Study type	Interventional
Source	University of Regina
Contact	Cameron Mang, PhD
Phone	306-585-4066
Email	cameron.mang@uregina.ca
Status	Recruiting
Phase	N/A
Start date	June 15, 2022
Completion date	April 30, 2025

View Details

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