Mechanism of Action of Ocrelizumab in Multiple Sclerosis

Status Recruiting

Clinical Trial Summary

Ocrelizumab is FDA approved for therapy of multiple sclerosis (MS). It depletes B cells and stops MS inflammation.

Clinical Trial Description

The study will investigate immune cell subsets, and how the cells are modified by this therapy over a 1-year period in 25 subjects. Blood will be drawn at baseline, 2 weeks, 6 mo, and 12 mo.

Immune subsets will be analyzed by flow cytometry. Data are analyzed with ANOVA with repeated measures. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03344094
Study type	Observational
Source	University of Chicago
Contact	anthony t reder, md
Phone	7737026204
Email	areder@neurology.bsd.uchicago.edu
Status	Recruiting
Phase	N/A
Start date	October 12, 2017
Completion date	December 31, 2019

View Details

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