Multiple Sclerosis (MS) Clinical Trial
Official title:
An Observational Pilot Study of Lumosity Computerized Cognitive Training in Subjects With Multiple Sclerosis
In collaboration with the Mercy MS Achievement Center, Lumos Labs is proposing an open-label, 12-month pilot study of computerized cognitive training as part of the cognitive wellness program in order to evaluate (1) the user experience of Lumosity in individuals with MS, and (2) the efficacy of Lumosity for improving cognitive outcomes in individuals with MS.
Approximately 50 current members of the Mercy MS Achievement Center will be provided with
12-month premium access Lumosity accounts. Study participants must be ≥18 years of age, and
currently members of the Achievement Center participating in the cognitive wellness program.
Those who consent will be provided with an account activation code and instructed on how to
sign up for Lumosity.
Upon creating an account, users would be asked to complete a short demographic survey
(Information About You, which includes age, sex, race/ethnicity, education, occupation) and
two additional short surveys: a Computer Experience Questionnaire and a Perceptions of Brain
Training questionnaire. In addition, participants will be assessed with the Montreal
Cognitive Assessment (MOCA), and be directed to take the Brain Performance Test (on a laptop
or desktop computer) within the first 7 days of creating their account. If not conducted
within the previous 3 months, participants would also be required to have the following
assessments at baseline (i.e., within the first 7 days): Multiple Sclerosis
Neuropsychological Questionnaire (MSNQ), Multiple Sclerosis Impact Scale-29 (MSIS-29), and
Beck Depression Inventory (BDI). After one week of using Lumosity, and then every other
month for 12 months, participants would be asked to complete a short questionnaire about
their experience with Lumosity. Every 3 months, participants would repeat the BPT, MSNQ, and
BDI; and every 6 months, they would repeat the MSIS. Finally, at the end of the study, the
end of the study they would also repeat the MOCA.
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