Comparison of Intermittent vs. Continuous Walking in MS

Multiple Sclerosis, Endurance Clinical Trial

Official title:

The Effect of Intermittent vs. Continuous Walking Training on Walking Endurance and Fatigue in People With Multiple Sclerosis: a Randomized, Crossover Trial.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02726373
• Other study ID #: INTCON1
• Status: Completed
• Phase: N/A
• First received: March 30, 2016
• Last updated: March 31, 2016
• Start date: January 2013
• Est. completion date: December 2014

Study information

• Verified date: March 2016
• Source: Hunter College
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

Objective: To compare effects of an intermittent and continuous walking program on walking endurance and fatigue in people with multiple sclerosis (MS).A randomized crossover prospective method was used.The intervention consisted of eight 6-minute-long walks (2x/week for 4 weeks). The continuous condition consisted of 6 continuous minutes of walking. The intermittent condition consisted of three 2-minute bouts with 2-minute rests. After a 4-week detraining period, participants performed the second training condition.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: December 2014
• Est. primary completion date: December 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Positive diagnosis of MS

• Ambulatory for at least 6 minutes with or without an assistive device (e.g. cane, crutches or orthotics)

• Ability to read, understand, and sign an informed consent form

Exclusion Criteria:

• Evidence of exacerbation in the prior three months as defined by a treating physician

• Orthopedic or cardiovascular condition that would interfere with ability to walk for 6 continuous minutes,

• Currently being on an active physical rehabilitation program

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Multiple Sclerosis
• Multiple Sclerosis, Endurance
• Sclerosis

Intervention

Other:
• type of walking
Subjects walked either intermittently or continuously twice a week for 4 weeks, then crossed over

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Hunter College

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pre to post change in 6 Minute walk test distance		4 weeks	No
Secondary	Visual Analog Scale of fatigue	Measurements to be taken at baseline and after each 4 week intervention	4 weeks	No