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Multiple Pulmonary Nodules clinical trials

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NCT ID: NCT03872362 Completed - Neoplasms Clinical Trials

Radiomics Multifactorial Biomarker for Pulmonary Nodules

RMBPN
Start date: July 11, 2018
Phase:
Study type: Observational

The investigators aim to investigate the utility of radiomics to differentiate malignant nodules from benign nodules and invasive adenocarcinoma from non-invasive adenocarcinoma.

NCT ID: NCT03845764 Completed - Lung Cancer Clinical Trials

Can a Pulmonologist Reliably Assess the Tumor Burden on ROSE Slides Obtained From Pulmonary Nodules and Lymphadenopathy

Start date: February 18, 2019
Phase:
Study type: Observational

The study is aimed at verifying if a pulmonologist can reliably assess the tumor burden for the extractive molecular analysis in ROSE samples obtained with endoscopic sampling procedures from intrathoracic lymphadenopathy and pulmonary nodules.

NCT ID: NCT03795181 Completed - Clinical trials for Multiple Pulmonary Nodules

Prediction Model for Multiple Pulmonary Nodules

Start date: January 1, 2019
Phase:
Study type: Observational

This study compares the sensitivity, specificity and accuracy of radiologists, thoracic surgeons and a predictive model (PKUM model) to discriminate malignancy from benign nodules in patients with multiple pulmonary nodules.

NCT ID: NCT03753724 Completed - Lung Cancer Clinical Trials

IDEAL: Artificial Intelligence and Big Data for Early Lung Cancer Diagnosis Study

IDEAL
Start date: August 29, 2018
Phase:
Study type: Observational

This study aims to test the use of novel CT image analysis techniques to enable a better characterisation of small pulmonary nodules. The study will incorporate solid and predominantly solid nodules of 5-15 mm scanned using a variety of scanner types, imaging protocols and patient populations. The investigators hope that the new image processing techniques will improve the accuracy of lung nodule analysis which will in turn reduce the number of unnecessary investigations for benign nodules and may increase the accuracy of the early diagnosis of lung cancer in malignant nodules. This study aims to test this novel analysis software to subsequently allow validation.

NCT ID: NCT03731156 Completed - Clinical trials for Invasive Fungal Infections

Granulomatous Pneumocystis Pneumonia

NC
Start date: June 1, 2018
Phase:
Study type: Observational

The intra-alveolar form of Pneumocystis jiroveci pneumonia (PjP) is a common pathology in immunocompromised patients, particularly those infected with HIV. The diagnosis is based on the detection of Pj in a LBA. Intra-tissue granulomatous form (PGP) is a rare entity observed in non-HIV immunocompromised patients. In this case, the LBA is mostly non-contributory and the diagnosis is based solely on the detection of cysts on histological examination on biopsy of a pulmonary nodule. For many years, it has been clearly demonstrated that the use of a specific PCR clearly improves the biological diagnosis of PcP. However, in case of granulomatous form this method is not implemented because the diagnostic hypothesis is not mentioned. In 2018, two cases of PGP were diagnosed at 3-month intervals at Montpellier University Hospital Center. The diagnostic confirmation was obtained with PCR Pj. In this context the investigators will investigate the interest of implementing PCR Pj on biopsies on pulmonary nodules from hospitalized patients between 2015 and 2018. In all selected patients, histopathological aspect of the nodule was compatible with a PGP and, no other diagnosis has been confirmed (infectious, tumoral, inflammatory ...). Finally, 17 patients were selected to check retrospectively, if the presence of Pj could be at the origin of the pathology.

NCT ID: NCT03716284 Completed - Clinical trials for Peripheral Pulmonary Nodules

ENB for the Diagnosis of PPNs:a Real World Study

Start date: March 20, 2019
Phase:
Study type: Observational

The study is designed as a multi-center prospective trial of ENB for the diagnosis of peripheral pulmonary nodules in the real world. The purpose of the study is to identify the optimal method of using ENB.

NCT ID: NCT03649906 Completed - Clinical trials for Pulmonary Nodule, Solitary

A Clinical Study of Optimized CT-guided Pulmonary Nodule Microcoil Localization Technique

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

In the early stage of the study, the CT-guided micro-coil locating method for pulmonary small nodules was optimized. This study will use a single set of target values non-randomized controlled trials to evaluate the safety and effectiveness of the optimized pre-loaded micro-coil locating method in pulmonary small nodules.

NCT ID: NCT03633006 Completed - Clinical trials for Lung Cancer (Diagnosis)

Blood Sample Collection in Subjects With Pulmonary Nodules or CT Suspicion of Lung Cancer or Pathologically Diagnosed Lung Cancer

Start date: April 11, 2016
Phase:
Study type: Observational

The primary objective of this study is to obtain de-identified, clinically characterized, whole blood specimens for use in assessing new biomarkers for the detection of neoplasms of the lung. Subjects will be men and women, 35 years of age and older, with a CT confirmed nodule measuring 6-30 mm.

NCT ID: NCT03591445 Completed - Clinical trials for Pulmonary Nodule, Solitary

Is Bronchoscopy Necessary in the Preoperative Workup of GGO Lung Cancer?(ECTOP-1005)

Start date: November 6, 2018
Phase: N/A
Study type: Interventional

This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1005). It aims to evaluate the role of flexible bronchoscopy in the pre-operative workup of ground glass opacity featured lung cancer. All enrolled patients receive the flexible bronchoscopy examination before surgery. Investigators observe the intra-bronchial findings of bronchoscopy and the impact of these findings on established surgical plan.

NCT ID: NCT03420885 Completed - Pulmonary Nodules Clinical Trials

Effects of Ba Duan Jin for Patients With Pulmonary Nodules

Start date: February 18, 2017
Phase: N/A
Study type: Interventional

Many researches shows that Ba Duan Jin has clinical efficacy on cancer rehabilitation, respiratory diseases, psychological health, quality of life and so on. Studies examining the effects of Ba Duan Jin on patients with pulmonary nodules are sparse. Therefore, the aims of the present study are: 1) to examine the effects of Ba Duan Jin on physical and psychological condition, and 2) to examine the effects of Ba Duan Jin on quality of life.