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Clinical Trial Summary

The purpose of this study is to assess of the Safety and Effects of Stereotactic Ablation Radiotherapy (SABR) combined with Sintilimab in early inoperable synchronous Multiple Primary Lung Cancer (sMPLC)


Clinical Trial Description

Stereotactic ablation radiotherapy (SABR) was performed sequentially on the primary and secondary lesions. 50Gy/4F or 70Gy/10F were used according to the specific location of the tumor. Immunotherapy was started 2 weeks after the end of radiotherapy. Sintilimab : 200 mg intravenously, Q3W every cycle , given on the D1 of each cycle, and total of 4 cycles. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04840758
Study type Interventional
Source The First Affiliated Hospital of Xiamen University
Contact Deng Chong, MD
Phone 8605922139531
Email dengchongxm@163.com
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date June 2021
Completion date April 2023

See also
  Status Clinical Trial Phase
Recruiting NCT05053802 - Efficiency and Safety of Microwave Ablation Plus Immune Checkpoint Inhibitor for Patients With Multiple Primary Lung Cancer: A Open, Multi-center, Phase II Clinical Trial Phase 2
Recruiting NCT05662553 - ENB Guided MWA Combined With VATS Versus Sequential Surgery for Synchronous Bilateral Multiple Primary Lung Nodules N/A