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A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma — iMMagine-3  

Multiple Myeloma Clinical Trial

Official title:
A Phase 3, Randomized, Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Multiple Myeloma

Clinical Trial Summary

The goal of this study (iMMagine-3) is to compare the study drug, anitocabtagene autoleucel to standard of care therapy (SOCT) in participants with relapsed/refractory multiple myeloma who have received 1 to 3 prior lines of therapy, including an anti-CD38 monoclonal antibody and an immunomodulatory drug. The primary objective of this study is to compare the efficacy of anitocabtagene autoleucel versus SOCT in participants with RRMM as measured by progression-free survival (PFS) per blinded independent review committee (IRC).

Clinical Trial Description

After completing the treatment period, all participants who will receive anitocabtagene autoleucel, will be followed in the post-treatment follow-up period. Thereafter, participants will transition to a separate long-term follow-up study (KT-US-982-5968) to continue follow-up out to 15 years. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06413498
Study type Interventional
Source Gilead Sciences
Contact Medical Information
Phone 844-454-5483(1-844-454-KITE)
Email medinfo@kitepharma.com
Status Not yet recruiting
Phase Phase 3
Start date October 2024
Completion date July 2031
View Details
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