Multiple Myeloma Clinical Trial
Official title:
A Phase II Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab for Patients With Monoclonal Gammopathy of Renal Significance (MGRS)
The purpose of this study is to find out whether cyclophosphamide, bortezomib, dexamethasone (CyBorD) with daratumumab SC is a safe treatment combination for MGRS-associated kidney disease including cast nephropathy associated with multiple myeloma. In addition, the researchers will find out whether the study drug combination is an effective treatment for these conditions.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
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Phase 1 | |
| Completed |
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| Completed |
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Phase 1/Phase 2 | |
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N/A | |
| Recruiting |
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Phase 3 | |
| Active, not recruiting |
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MCARH109 Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of Multiple Myeloma
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Phase 1 | |
| Recruiting |
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The Safety and Efficay Investigation of CAR-T Cell Therapy for Patients With Hematological Malignancies
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N/A | |
| Active, not recruiting |
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Phase 3 | |
| Recruiting |
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Phase 2 | |
| Completed |
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Myeloid-Derived Suppressor Cells and Checkpoint Immune Regulators' Expression in Allogeneic SCT Using FluBuATG
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Phase 1 | |
| Recruiting |
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|
Phase 2 | |
| Terminated |
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NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)
|
Phase 1 | |
| Completed |
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First-in- Human Imaging of Multiple Myeloma Using 89Zr-DFO-daratumumab, a CD38-targeting Monoclonal Antibody
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Phase 1/Phase 2 | |
| Completed |
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Phase 1/Phase 2 | |
| Active, not recruiting |
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Study of Oral LOXO-338 in Patients With Advanced Blood Cancers
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Phase 1 | |
| Active, not recruiting |
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A Study to Determine the Recommended Dose and Regimen and to Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination With Standard Treatments in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) and Newly Diagnosed Multiple Myeloma (NDMM)
|
Phase 1/Phase 2 | |
| Active, not recruiting |
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Denosumab for High Risk SMM and SLiM CRAB Positive, Early Myeloma Patients
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Phase 2 | |
| Withdrawn |
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A Study of Ixazomib, Thalidomide and Dexamethasone in Newly Diagnosed and Treatment-naive Multiple Myeloma (MM) Participants Non-eligible for Autologous Stem-cell Transplantation
|
Phase 2 | |
| Recruiting |
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Clinical Study to Evaluate the Safety and Efficacy of IM21 CAR-T Cells in the Treatment of Elderly Patients With Relapsed or Refractory Multiple Myeloma
|
Phase 1 | |
| Completed |
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CART-BCMA Cells for Multiple Myeloma
|
Phase 1 |